medigraphic.com
ISSN 2007-3178 (Print)
Asociación Mexicana de Cirugía Bucal y Maxilofacial, Colegio Mexicano de Cirugía Bucal y Maxilofacial, A.C.

2026, Number 1

<< Back Next >>

Rev Mex Cir Bucal Maxilofac 2026; 22 (1)

Salivary gland oncocytoma. Case report and literature review

Avilés HIA, Oliman HZM, Chávez PT

Language: English
References: 15
Page: 26-31
PDF size: 1976.77 Kb.


ABSTRACT

Introduction: oncocytoma is a rare benign neoplasm with clinical and imaging characteristics similar to other benign glandular tumors, representing 2% of them. Histopathologically, oncocytic cells with eosinophilic granular cytoplasm, abundant mitochondria, and rounded nuclei with characteristic prominent nucleoli are observed. Objective: to present the diagnostic and therapeutic approach to a parotid oncocytoma with a literature review describing its differential characteristics. Case report: a 58-year-old female patient with a symptomatic swelling in the right preauricular region with a six-month evolution. Simple and contrast-enhanced tomography revealed a spherical iso-dense lesion associated with the superficial lobe of the parotid gland. Surgical protocol was established to perform a conservative superficial parotidectomy for lesion excision. Results: postoperative evolution was favorable, without evidence of facial nerve injury or recurrence of the injury at 24 months of follow-up. Conclusions: the identification of oncocytic cells by histopathological study is the key to the differential diagnosis of oncocytoma compared to other salivary gland tumors with similar clinical symptoms and clave para el diagnóstico diferencial del oncocitoma frente a otros tumores de glándulas salivales con clínica e imagen similares, su tratamiento es quirúrgico y requiere vigilancia a largo plazo por el riesgo de recidiva.


REFERENCES

  1. Alberto PL, Ashim S, Megan K, Wei Z, Nestor G, Matthew Z etal. Salivary gland oncocytomas. A systematic review. Head NeckPathol. 2024; 18 (1): 126. doi: 10.1007/s12105-024-01730-6.

  2. Imran S, Allen A, Shokouh-Amiri M, Garzon S, Saran N. Parotidoncocytoma: CT and pathologic correlation of a rare benign parotidtumor. Radiol Case Rep. 2019; 15 (1): 31-34. doi: 10.1016/j.radcr.2019.10.003.

  3. Zhu W, Zhang Y, Li F, Li G, Zhang P, Fang H, Bian L. Case of clearcelloncocytoma of parotid gland and literature review. Hua Xi KouQiang Yi Xue Za Zhi. 2024; 42 (1): 126-134. English, Chinese. doi:10.7518/hxkq.2024.2023185.

  4. Singh J, Chandra A, Srilatha T, Jain T, Raja D, Agrawal R.Oncocytoma of the parotid gland: a rare benign tumour. J OralMaxillofac Pathol. 2023; 27 (Suppl 1): S41-S44. doi: 10.4103/jomfp.jomfp_437_21.

  5. Rivera RD, Nelson BL. Sine qua non: oncocytoma. Head NeckPathol. 2022; 16 (4): 1167-1171. doi: 10.1007/s12105-022-01462-5.

  6. Miladinovic D, Trautman J, Yabe T. A cautionary tale: a case reportdescribing a benign parotid oncocytoma diagnosed as metastaticsquamous cell carcinoma on fine needle aspirate. Cureus. 2023;15 (12): e50853.

  7. Jurczyk M, Peevey JF, Vande Haar MA, Lin X. Pitfalls of fineneedleaspiration cytology of parotid membranous basal celladenoma-A review of pitfalls in FNA cytology of salivary glandneoplasms with basaloid cell features. Diagn Cytopathol. 2015;43 (5): 432-437.

  8. Bhushan LCK. Submandibular gland oncocytoma: a rare tumorcase series-its diagnosis and treatment based on clinicopathology.J Maxillofac Oral Surg. 2023; 22 (1): 127-131. doi: 10.1007/s12663-022-01775-6.

  9. Bullock MJ, Jiang XS. Top ten oncocytic head and neck lesions tocontemplate. Head Neck Pathol. 2023; 17 (1): 53-65. doi: 10.1007/s12105-022-01520-y.

  10. Lv K, Cao X, Geng D, Zhang J. Imaging features of parotid glandoncocytoma: a case series study. Gland Surg. 2021; 10 (3): 870-876. doi: 10.21037/gs-20-790.

  11. Prabhakar P, Rao N, Kairanna NV, Shetty S, Singh VK. Oncocyticsalivary gland tumours: cytological features and diagnostic pitfalls.Indian J Otolaryngol Head Neck Surg. 2022; 74 (Suppl 3): 6112-6118. doi: 10.1007/s12070-021-02764-w.

  12. Lubin D, Song S, Zafar HM, Baloch Z. The key radiologic andcytomorphologic features of oncocytic and oncocytoid lesions ofthe salivary gland. Diagn Cytopathol. 2019; 47 (6): 617-636. doi:10.1002/dc.24175.

  13. Hamada S, Fujiwara K, Hatakeyama H, Homma A. Oncocytoma ofthe parotid gland with facial nerve paralysis. Case Rep Otolaryngol.2018; 2018: 7687951. doi: 10.1155/2018/7687951.

  14. Sepúlveda I, Platín E, Spencer ML, Mucientes P, Frelinghuysen M,Ortega P, Ulloa D. Oncocytoma of the parotid gland: a case reportand review of the literature. Case Rep Oncol. 2014; 7 (1): 109-116.doi: 10.1159/000359998.

  15. Peraza LA, Umorin M, Shrestha M, Abad VC, Wright J. A possibleassociation of salivary gland tumors and oral lesions with Birt-Hogg-Dube syndrome: a systematic review. Head Neck Pathol.2024; 18 (1): 52. doi: 10.1007/s12105-024-01657-y.




2020     |     www.medigraphic.com