López AFG, Jiménez CC, González PK

Language: Spanish
References: 16
Page: 35-42
PDF size: 334.18 Kb.

ABSTRACT

Introduction: sepsis-induced acute kidney injury (AKI) is a syndrome caused by infections or the body's response to them, where diagnosis using serum creatinine and urine output may be limited. Objective: to evaluate the usefulness of the renal resistance index (RRI) and interleukin-6 (IL-6) compared to the ARMO score for predicting AKI in critically ill patients with sepsis. Material and methods: a longitudinal, prospective, analytical study with non-probability sampling of consecutive patients with sepsis admitted to the Intensive Care Unit (ICU) of the UMAE del Bajío. Patients underwent evaluation using the ARMO score, serum IL-6 levels, and RRI upon ICU admission between March and August 2025. Results: forty-seven patients with sepsis were included. The mean age was 48.7 years; there was a slight predominance of women (53.19%). The most frequent comorbidities were systemic hypertension (48%) and type 2 diabetes mellitus (34.04%). The study identified age, male sex, need for vasopressors, thrombocytopenia, presence of liver failure, elevated creatinine, high IL-6 levels, and ARMO scores as factors associated with increased mortality in patients with sepsis. A moderate positive correlation was observed between IL-6 levels and the severity of AKI. The IRR showed limited diagnostic capacity for predicting AKI (AUC = 0.60), while the ARMO score demonstrated excellent performance in predicting sepsis-associated AKI with a cutoff point of 5 points and an AUC of 0.96. Conclusion: the ARMO score proved to be the most reliable marker for identifying patients at risk of developing AKI in the context of sepsis.

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