2026, Number 1
<< Back Next >>
Rev Mex Pediatr 2026; 93 (1)
Preseptal cellulitis and cerebritis as complications of pansinusitis
Muñoz-Álvarez NA, Terán-Jaramillo AP
Language: Spanish
References: 20
Page: 27-31
PDF size: 1372.09 Kb.
ABSTRACT
Introduction: pansinusitis can lead to orbital and intracranial complications, which are infrequent but can be serious.
Case presentation: a previously healthy 13-year-old male adolescent presented with persistent frontal headache and three days of fever, followed by left eyelid edema and erythema. Imaging studies revealed preseptal cellulitis secondary to pansinusitis. On the fifth day of hospitalization, despite initial antibiotic treatment, he experienced a focal motor seizure and altered mental status. Magnetic resonance imaging identified left frontal cerebritis, and broad-spectrum antimicrobial and anticonvulsant therapy was initiated. Endoscopic sinus surgery was also performed. He completed four weeks of antibiotic therapy with good clinical progress and no neurological sequelae.
Conclusions: this case highlights the importance of timely detection of sinusitis complications and the need for a multidisciplinary approach to improve the prognosis for these patients.
REFERENCES
Leung AK, Hon KL, Chu WC. Acute bacterial sinusitis in children: an updated review. Drugs Context. 2020; 9: 2020-9-3.
Conway SJ, Mueller GD, Shaikh N. Antibiotics for acute sinusitis in children: a meta-analysis. Pediatrics. 2024; 153(5): e2023064244.
Ramadan HH, Chaiban R, Makary C. Pediatric rhinosinusitis. Pediatr Clin North Am. 2022; 69(2): 275-286.
Raponi I, Giovannetti F, Buracchi M, Priore P, Battisti A, Scagnet M et al. Management of orbital and brain complications of sinusitis: a practical algorithm. J Craniomaxillofac Surg. 2021; 49(12): 1124-1129.
Bedoya GJD, Vanegas RGA, Herrera NP, Restrepo PM, Escobar HM, Osorio MOJ. Guía para el diagnóstico y tratamiento de rinosinusitis en niños. Acta Otorrinolaringol Cir Cabeza Cuello. 2024; 52(4): 611-636.
Otto WR, Paden WZ, Connors M, Joerger T, Buzi A, Rizzi M et al. Suppurative intracranial complications of pediatric sinusitis: a single-center experience. J Pediatr Infect Dis Soc. 2021; 10(3): 309-316.
Wilcox J, Lobo D, Anderson S. Sinusitis. Prim Care. 2025; 52(1): 87-97.
Hallak B, Bouayed S, Ghika JA, Teiga PS, Alvarez V. Management strategy of intracranial complications of sinusitis: our experience and review of the literature. Allergy Rhinol. 2022; 13: 21526575221125031.
Zhao EE, Koochakzadeh S, Nguyen SA, Yoo F, Pecha P, Schlosser RJ. Orbital complications of acute bacterial rhinosinusitis in the pediatric population: A systematic review and meta-analysis. Int J Pediatr Otorhinolaryngol. 2020; 135: 110078.
Neves JF, Simoes JF, Paiva S, Maricato F, Silva LF. Orbital complications in pediatric acute sinusitis: eight-year experience. Birth Growth Med J. 2021; 30(4): 207-212.
Saltagi MZ, Rabbani CC, Patel KS, Wannemuehler TJ, Chundury RV, Illing EA et al. Orbital complications of acute sinusitis in pediatric patients: management of chandler III patients. Allergy Rhinol. 2022; 13: 21526575221097311.
Yeh CH, Chen WC, Lin MSF, Huang HT, Chao SC, Lo YC. Intracranial brain abscess preceded by orbital cellulitis and sinusitis. J Craniofac Surg. 2010; 21(3): 934-936.
Constantin F, Niculescu PA, Petre O, Balasa D, Tunas A, Rusu I et al. Orbital cellulitis and brain abscess: rare complications of maxillo-spheno-ethmoidal rhinosinusitis. Rom J Ophthalmol. 2017; 61(2): 133-136.
Flanders TM, Kumar NK, Zhao C, Joerger TA, Huh JW, Buzi A et al. Intracranial complications secondary to acute bacterial sinusitis requiring neurosurgical intervention before and after the onset of the COVID-19 pandemic. J Neurosurg Pediatr. 2024; 34(5): 479-488.
Smiljkovic M, Tat J, Richardson SE, Campigotto A, Cushing SL, Wolter NE et al. A 20-year study of intracranial pyogenic complications of sinusitis in children. Pediatr Infect Dis J. 2024; 43(2): 91-96.
Werner MT, Gottfried JS, Awan BEZ, Pollack AZ, Tong CCL, Fastenberg JH et al. Intracranial and orbital complications of sinusitis: a review of rhinologic and multidisciplinary management principles. Ear Nose Throat J. 2025; 1455613251342857.
Nagaraj UD, Koch BL. Imaging of orbital infectious and inflammatory disease in children. Pediatr Radiol. 2021; 51(7): 1149-1161.
Galstyan-Minasova V, Alamar-Velázquez A, Ibáñez-Alcañiz I, Lesmas-Navarro MJ, Armengot-Carceller M, Galstyan-Minasova V et al. Complicaciones de la sinusitis aguda en edad pediátrica. Rev ORL. 2025; 16(1): 13-20.
Romano FR, Anselmo-Lima WT, Kosugi EM, Sakano E, Valera FCP, Lessa M et al. Rhinosinusitis: evidence and experience-2024. Braz J Otorhinolaryngol. 2025; 91(5): 101595.
Kole MT, Kivrak U, Cag Y, Mehmetoglu S, Karaaslan A, Cetin C et al. Preseptal and orbital cellulitis in children: a five-year single-center experience. South Clin Ist Euras. 2022; 33(4): 360-365.