Limón SJ, Barbabosa JA, Palestino RG, Hernández FSE

Language: Spanish
References: 14
Page: 28-33
PDF size: 2146.97 Kb.

ABSTRACT

Introduction: appendiceal mucinous neoplasms are uncommon entities that may present with nonspecific clinical manifestations and mimic gynecologic conditions seen in the pelvic region, which complicates preoperative identification and increases the likelihood of imaging-based misdiagnosis. The aim of this article is to describe a case of low-grade appendiceal mucinous neoplasm incidentally diagnosed during gynecologic surgery and to analyze its diagnostic and clinical implications. Case description: a 42-year-old woman with abnormal uterine bleeding secondary to uterine leiomyomatosis underwent a total abdominal hysterectomy. The clinical, surgical, anatomopathological, and immunohistochemical findings were reviewed, as well as the postoperative evolution. An unexpectedly macroscopic abnormality of the cecal appendix was identified, and a concomitant appendectomy was therefore performed. Histopathological study revealed a low-grade mucinous appendicular neoplasm confined to the appendix, with clear surgical margins and associated endometriosis. SATB2 was positive and PAX8 and estrogen receptors were negative, confirming an appendiceal origin. The postoperative course was favorable, with no complications or need for adjuvant treatment. Conclusions: appendiceal pathology should be considered in the differential diagnosis of pelvic masses. A multidisciplinary approach may help establish an accurate diagnosis and guide appropriate management.

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