2026, Number 1
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Enf Infec Microbiol 2026; 46 (1)
Candidal intertrigo due to misuse of corticosteroids
Mendoza-Gómez JM, Salazar-López MD, Barrera-Hernández S
Language: Spanish
References: 10
Page: 48-51
PDF size: 302.51 Kb.
ABSTRACT
Intertrigo is a common inflammatory condition of the skin folds, caused by persistent friction between skin surfaces,
exacerbated by moisture, increased local pH, and temperature. Factors that facilitate colonization and infection
by Candida albicans include obesity, type 2 diabetes, immunosuppression, hyperhidrosis, incontinence, and poor
hygiene. Clinically, it manifests as erythematous, moist, painful, and pruritic plaques located in the groin, armpits,
and inframammary region. Diagnosis is clinical, supported in some cases by Wood’s lamp examination and koh skin
scrapings. Treatment includes lifestyle modifications, management of comorbidities, topical antifungals (azoles),
and, in selected cases, limited use of corticosteroids.
We present the case of a 36-year-old female patient with type 2 diabetes mellitus under treatment, who
presented with skin lesions in skin folds and self-medicated with prednisone.
conclusion. It is necessary to educate patients to avoid self-medication, which can lead to complications.
REFERENCES
Official reprint from UpToDate www intertrigo.
Manzano Gayosso, P., Hernández Hernández, F., RománArgüero, P. et al., “Intertrigo en pacientes hospitalizadosen el servicio de Medicina Interna de un hospital de laCiudad de México. Causa fúngica y sensibilidad antifúngicain vitro”, Dermatol Rev Mex, 2024, 68 (3): 315-324.
Voegeli, D., “Prevention and management of moisture-associatedskin damage”, Nurs Stand, 2019, 34 (2): 77-82.
Ali, S.M. y Yosipovitch, G., “Skin pH: from basic scienceto basic skin care”, Acta Derm Venereol, 2013, 93 (3):261-267.
Feldmeyer, L., Werner, S., French, L.E. y Beer, H.D.,“Interleukin-1, inflammasomes and the skin”, Eur J CellBiol, 2010, 89 (9): 638-644.
Rippke, F., Berardesca, E. y Weber, T.M., “pH and microbialinfections”, Current Problems in Dermatology(Suiza), 2018, 54: 87-94.
Janniger, CK., Schwartz, R.A., Szepietowski, J.C. yReich, A., “Intertrigo and common secondary skin infections”,Am Fam Physician, 2005, 72 (5): 833-838.
Brennan, M.R., Milne, C.T., Agrell-Kann, M. y Ekholm,B.P., “Clinical evaluation of a skin protectant for themanagement of incontinence-associated dermatitis:an open-label, nonrandomized, prospective study”, JWound Ostomy Continence Nurs, 2017, 44 (2): 172-180.
Castillo Rangel, J.M., Miranda Alvarado-Benítez, A.Vega, D.C., Juárez Durán, R. y Arenas, R., “Intertrigopor Candida spp. de grandes pliegues. Informe de 45casos”, Dermatología Cosmética, Médica y Quirúrgica,2022, 20 (1), pp. 12-15.
Romanelli, M., Voegeli, D., Colboc, H., Bassetto, F., Janowska,A., Scarpa, C. y Meaume, S., “The diagnosis,management and prevention of intertrigo in adults: areview”, J Wound Care, 2023, 32 (7): 411-420.