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2026, Number 1

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Dermatología Cosmética, Médica y Quirúrgica 2026; 24 (1)

Trichodynia as the initial manifestation of early lichen planopilaris without evident trichoscopic correlates: a case report

Vera RV, Benítez HAK
Full text How to cite this article

Language: Spanish
References: 12
Page: 46-50
PDF size: 176.48 Kb.


Key words:

trichodynia, scalp dysesthesia, lichen planopilaris, trichoscopy, neuropathic pain.

ABSTRACT

Trichodynia is a symptom characterized by pain or discomfort of the scalp, commonly associated with inflammatory alopecias, although it may occur in the absence of specific clinical or trichoscopic findings. Its pathophysiology remains unclear and poses diagnostic and therapeutic challenges, particularly in cases of clinicopathological discordance.
We report the case of an 18-year-old female patient presenting with predominant scalp pain localized to the vertex. A prior scalp biopsy suggested early-stage lichen planopilaris. Clinical and trichoscopic evaluations were performed at baseline and during follow-up, and treatment was directed toward the predominant symptom. Clinical examination revealed mild erythema and minimal interfollicular scaling. Trichoscopy showed diffuse erythema, superficial telangiectasias, and preserved follicular openings, without features of active cicatricial alopecia. Treatment with topical clobetasol and venlafaxine 75 mg/day was initiated. After two months, the patient experienced a clinically significant improvement in scalp pain, with resolution of erythema and marked reduction of scaling on follow-up trichoscopy. Transient insomnia was the only reported adverse effect.
Trichodynia may be the predominant manifestation even in the absence of evident clinical or trichoscopic inflammatory activity. In cases of clinicopathological discordance, prioritizing symptom-oriented treatment, including centrally acting agents such as venlafaxine, may be an effective strategy and help avoid unnecessary aggressive immunomodulatory therapies.


REFERENCES

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  2. Trüeb RM, Starace MVR, Piraccini BM, Rezende HD, ReisGavazzoni Dias MF. Trichodynia Revisited. Skin AppendageDisord 2021;7(6):449–453.

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  8. Doche I, Wilcox GL, Ericson M, et al. Evidence for neurogenicinflammation in lichen planopilaris and frontal fibrosing alopeciapathogenic mechanism. Exp Dermatol 2020;29(3):282–285.

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Dermatología Cosmética, Médica y Quirúrgica. 2026;24