2026, Number 2
<< Back Next >>
Dermatología Cosmética, Médica y Quirúrgica 2026; 24 (2)
Scalp contact dermatitis: a review article
Herz RME, Contreras HMM, Salazar HIM
Language: Spanish
References: 32
Page: 279-295
PDF size: 558.09 Kb.
ABSTRACT
BACKGROUND: Contact dermatitis of the scalp is frequently
underdiagnosed. The scalp is repeatedly exposed to allergens
and irritants due to the use of hair accessories and
hair care products. Its anatomical characteristics confer certain
resistance to the development of inflammatory lesions,
often resulting in minimal involvement of the scalp itself,
with greater involvement of adjacent areas. This pattern
complicates recognition and leads to delays in diagnosis
and treatment.
MATERIALS AND METHODS: A narrative review of the literature
was conducted, including original articles, systematic
reviews, and relevant case series on contact dermatitis
of the scalp. Epidemiological aspects, the most frequent
causative agents, clinical manifestations, histopathological
findings, the usefulness of patch testing, and current therapeutic
approaches were analyzed.
RESULTS: The literature review showed that contact dermatitis
of the scalp is mainly associated with the use of hair
cosmetic products, with hair dyes being the most frequent
cause in some studies. Other reported allergens include
preservatives, fragrances, and metals. Clinically, erythema,
scaling, and pruritus predominate, often with typical patterns
that complicate the differential diagnosis. Patch testing
is essential to confirm the diagnosis, identify potential
causative agents, and thereby avoid exposure, reducing
disease recurrence.
CONCLUSIONS: Contact dermatitis of the scalp represents
a diagnostic challenge that requires a high index of clinical
suspicion. Patch testing remains the diagnostic gold standard. A comprehensive approach that includes identification
and avoidance of the causative agent, as well as
the use of anti-inflammatory treatments, allows for the
adequate disease control and improves patients´ quality
of life.
REFERENCES
Li Y, Li L. Contact dermatitis: classifications and management.Clin Rev Allergy Immunol. 2021;61:245–281.
Karim M, Klein EJ, Nohria A, Taiwo D, Adotama P, Cohen D,Shapiro J, Milam E, Lo Sicco K. Potential for Allergic ContactDermatitis in Popular Hair Care Practices and Ingredients.Dermatitis. 2023;34(6):484-491
Huynh M, Sheehan MP, Chung M, Zirwas M, Feldman SR.Scalp. In: Lewallen R, Clark A, Feldman SR, editors. Clinicalhandbook of contact dermatitis: diagnosis and management bybody region. Boca Raton: CRC Press; 2014. p. 6–12.
Hwang JC, Beatty CJ, Khobzei K, Kazlouskaya V. Allergic contactdermatitis of the scalp: a review of an underdiagnosed entity.Int J Womens Dermatol. 2024;10(3):e167.
Lyakhovitsky A, Carmeli G, Segal O, Solomon M, ShemerA, Barzilai A, Galili E. Scalp Allergic Contact Dermatitis: ARetrospective Analysisof Allergen Profiles and DistributionPatterns. Dermatitis. 2025:17103568251367790.
Encabo Durán B, Romero-Pérez D, Silvestre Salvador JF. AllergicContact Dermatitis Due to Paraphenylenediamine: An Update.Actas Dermosifiliogr. 2018;109(7):602-609.
Zahir A, Kindred C, Blömeke B, Goebel C, Gaspari AA. Toleranceto a Hair Dye Product Containing 2-Methoxymethyl-P-Phenylenediaminein an Ethnically Diverse Population of P-Phenylenediamine-Allergic Individuals. Dermatitis. 2016;27(6):355-361.
Arribas MP, Soro P, Silvestre JF. Dermatitis de contacto alérgicapor fragancias. Parte I. Actas Dermatosifilogr. 2012;103:874-879.
Alfalah M, Loranger C, Sasseville D. Alkyl Glucosides.Dermatitis. 2017;28(1):3-4.
Andersen, K.E., Mose, K.F. (2016). Preservatives. In:Johansen, J., Lepoittevin, JP., Thyssen, J. (eds) Quick Guideto Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47714-4_13
de Groot A, White IR, Flyvholm MA, Lensen G, Coenraads PJ.Formaldehyde-releasers in cosmetics: relationship toformaldehyde contact allergy. Part 2. Patch test relationship toformaldehyde contact allergy, experimental provocation tests,amount of formaldehyde released, and assessment of riskto consumers allergic to formaldehyde. Contact Dermatitis.2010;62(1):18-31.
Latorre N, Silvestre JF, Monteagudo AF. Dermatitis de contactoalérgica por formaldehído y liberadores de formaldehído[Allergic contact dermatitis caused by formaldehyde andformaldehyde releasers]. Actas Dermosifiliogr. 2011;102(2):86-97.
Warshaw EM, Boralessa Ratnayake D, Maibach HI,Sasseville D, Belsito DV, Zug KA, Fowler JF Jr., Taylor JS,Toby Mathias CG, Fransway AF, Deleo VA, Marks JG Jr, StorrsFJ, Pratt MD, Rietschel RL. Positive patch-test reactions toiodopropynyl butylcarbamate: retrospective analysis of northAmerican contact dermatitis group data, from 1998 to 2008.Dermatitis. 2010;21(6):303-10.
Soffer GK, Toh J, Clements S, Jariwala S. A case of chroniccontact dermatitis resulting from the use of blue hair dye.Contact Dermatitis. 2016;75(4):258-9.
Marks, James G., Jr., M.D.; Anderson, Bryan E., M.D.; DeLeo,Vincent A., M.D.Contact and Occupational Dermatology. 4thEd. Hardcover.2016.400p
Rodrigues-Barata AR, Conde-Salazar Gómez L. Methylisothiazolinoneand Methylchloroisothiazolinone-New insights. EMJDermatol. 2014;2:101-105.
García-Gavín J et al. Methylisothiazolinone, an emergingallergen in cosmetics? Contact Dermatitis. 2010, 63:96-101.
Johansen, J. D., Frosch, P. J., & Lepoittevin, J.-P. (2011). Contactdermatitis. Berlin: Springer.
Pham CT, Juhasz M, Lin J, Hashemi K, Honari G, MesinkovskaNA. Allergic Contact Dermatitis of the Scalp AssociatedWith Scalp Applied Products: A Systematic Review of TopicalAllergens. Dermatitis. 2022;33(4):235-248.
Bolognia JL, Jorizzo JL, Schaffer JV. Dermatology. 3rd ed.Philadelphia: Elsevier; 2012.
Hillen U, Grabbe S, Uter W. Patch test results in patients withscalp dermatitis: analysis of data of the Information Networkof Departments of Dermatology. Contact Dermatitis. 2007Feb;56(2):87-93
Schalock PC, Dunnick CA, Nedorost S, Brod B, Warshaw E,Mowad C, Scheman A; American Contact Dermatitis SocietyCore Allergen Series Committee. American Contact DermatitisSociety Core Allergen Series: 2020 Update. Dermatitis.2020;31(5):279-282.
Frosch P, Geier J, Uter W, Goossens A. Patch testing with thepatients’ own products. In: Johansen JD, et al., editors. Contactdermatitis. Berlin, Heidelberg: Springer-Verlag; 2011. p. 1113.
Goossens A. Contact allergic reactions to cosmetics. J Allergy(Cairo). 2011;2011:467071.
Starace M, Bruni F, Marcondes MT, Alessandrini A, PiracciniBM. The identification of trichoscopic features of allergicscalp contact dermatitis: a pilot-study of a single center. Ital JDermatol Venerol. 2023;158(4):334-340.
Makowska K, Golin´ska J, Sar-Pomian M, Rudnicka L. TrichoscopyFeatures of Allergic Contact Dermatitis of the Scalp: AProspective Case Series. Dermatitis. 2023;34(3):265-268.
Aleid NM, Fertig R, Maddy A, Tosti A. Common AllergensIdentified Based on Patch Test Results in Patients withSuspected Contact Dermatitis of the Scalp. Skin AppendageDisord. 2017;3(1):7-14.
LeFevre NM, Braudis K, Feigenbaum LS. Seborrheic dermatitis:diagnosis and treatment. Am Fam Physician. 2025;112(2):166-173.
Armstrong AW, Read C. Pathophysiology, clinical presentation,and treatment of psoriasis: a review. JAMA. 2020;323(19):1945-1960.
Fonacier L, Bernstein DI, Pacheco K, Holness DL,Blessing-Moore J, Khan D, Lang D, Nicklas R, Oppenheimer J,Portnoy J, Randolph C, Schuller D, Spector S, Tilles S, WallaceD; American Academy of Allergy, Asthma & Immunology;American College of Allergy, Asthma & Immunology; JointCouncil of Allergy, Asthma & Immunology. Contact dermatitis:a practice parameter-update 2015. J Allergy Clin Immunol Pract.2015;3(3 Suppl):S1-39.
Olbrich H, Sadik CD, Ludwig RJ, Thaçi D, Boch K. Dupilumabin Inflammatory Skin Diseases: A Systematic Review.Biomolecules. 2023;13(4):634.
Rivera-Ruiz I, Gil-Villalba A, Navarro-Triviño FJ. Exploring NewHorizons in Allergic Contact Dermatitis Treatment: The Roleof Emerging Therapies. Actas Dermosifiliogr. 2025;116(7):T731-T739.