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2026, Number 2

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Rev Mex Traspl 2026; 15 (2)

Six-year experience in the detection of BK virus infection by viruria in patients with acute renal graft dysfunction

Toledo-Sotelo JI, Rodríguez-Villanueva FL, Ortega-Rodríguez R, Rodríguez-Garduño LS, Espinoza-Pérez R, Benítez-Arvizu G, Cancino-López JD, Delgado-Colín G, Martínez-Mendoza ME, Bautista-Olayo R, Aranda-Osorio JR, H HJC

Language: Spanish
References: 22
Page: 61-67
PDF size: 832.12 Kb.


ABSTRACT

Introduction: infections continue to be one of the main complications in kidney transplantation (KT) and are directly related to the duration of the KT and a cause of morbidity and mortality. The objective is to show the incidence of BK virus cases due to viruria. Material and methods: a descriptive study was conducted of viruria studies in patients within the acute graft dysfunction (AGD) protocol. Patients were included from February 2019 to December 2024, with those with 107 copies considered positive. Descriptive statistics were performed with frequencies and percentages for qualitative variables and categorization of results. The SPSS version 26 statistical package was used. Results: 521 viruria tests were performed on patients enrolled in the ICD protocol. Twenty-two patients (4.22%) were positive, 421 patients (80.81%) were not detected, and 78 patients (14.97%) were detected without a positive criterion, ranging from 100 to fewer than 10 million copies. Conclusions: BK virus infection detected by viruria represented 4.22% of the total transplant patients studied by ICD. This type of testing allows for early detection and the implementation of measures that improve the prognosis for graft function. Hospitals that perform this type of testing must be equipped with the appropriate equipment and specialized personnel, as well as the knowledge of the associated risk factors in each case. Decoy cell cytology can be an alternative for those who do not have viruria and/or viremia at their centers.


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