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Órgano Oficial del Hospital Ángeles Health System

2026, Number P5

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Acta Med 2026; 24 (P5)

Survival of patients requiring renal replacement therapy in the Intensive Care Unit of Hospital Angeles Pedregal

Morales AJA, Martínez JIA, Esponda PJG

Language: Spanish
References: 16
Page: 517-521
PDF size: 444.91 Kb.


ABSTRACT

Introduction: acute kidney injury (AKI) is a common complication in critically ill patients and is associated with high morbidity and mortality. Renal replacement therapy with hemodialysis is frequently used, although the optimal timing for initiation remains controversial. Objective: to evaluate the survival outcomes of AKI patients requiring hemodialysis in the intensive care unit (ICU) at Hospital Ángeles Pedregal. Material and methods: this retrospective observational study included 40 patients aged ≥ 18 years with KDIGO stage 2 or 3 AKI who received RRT. Biochemical, clinical, and outcome parameters were compared based on renal recovery at discharge. Early initiation was defined as RRT initiated within 8 h of reaching KDIGO stage 2; late initiation was defined as RRT initiated in stage 3 with urgent indications. Results: 27.5% of patients achieved renal recovery before discharge. These patients required fewer dialysis sessions (1.8 ± 0.7 vs. 3.0 ± 1.1; p = 0.085). The serum creatinine and urea levels at discharge were significantly lower in the recovery group (p ‹ 0.05). Volume overload and vasopressor use were associated with lower recovery rates, although the differences were not statistically significant. Conclusion: earlier RRT initiation may favor renal recovery. Volume overload and hemodynamic instability are potential negative prognostic factors. Further prospective studies are needed to refine therapeutic strategies.


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