Vásquez REC, Epinoza LPS, López OMI, Irisson MI, Sánchez GT, Arias RM, García NAR

Language: Spanish
References: 19
Page: 543-547
PDF size: 2329.68 Kb.

ABSTRACT

Introduction: endoscopic endonasal transsphenoidal surgery has become the preferred approach for pituitary neuroendocrine tumors (PitNET), providing wide visualization and minimal invasiveness. However, nasal complications remain a relevant cause of postoperative morbidity. This study analyzed the incidence and management of nasal complications in patients undergoing endoscopic endonasal transsphenoidal resection of PitNET. Material and methods: a retrospective review of 20 patients who underwent endoscopic endonasal transsphenoidal surgery between 2022 and 2024 was performed. Nasal complications and their management were evaluated during follow-up. Results: the mean patient age was 47.4 years. Non-functioning adenomas were the most common histology (75%), and 85% were macroadenomas. The most frequent postoperative nasal event was early epistaxis (15%), followed by transient hyposmia (10%) and postoperative rhinitis (5%). No cases of meningitis, cerebrospinal fluid leak, or permanent olfactory loss were observed. All complications resolved with conservative management. Conclusions: nasal complications following endoscopic endonasal transsphenoidal surgery were infrequent, mild, and transient. Early postoperative epistaxis was the most common event, while olfactory alterations were reversible. Careful mucosal preservation, systematic nasal irrigation, and early otolaryngological follow-up are essential to minimize morbidity and optimize functional recovery.

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