2026, Number 4
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Rev Mex Pediatr 2026; 93 (4)
Descending flaccid paralysis clinically consistent with wound botulism
Luna-Mazzillo A, Mazzillo-Vega L
Language: Spanish
References: 23
Page: 166-170
PDF size: 768.51 Kb.
ABSTRACT
Introduction: wound botulism is a rare neuroparalytic disease
in pediatrics caused by botulinum toxin. Early recognition
poses a diagnostic challenge.
Objective: to describe the case
of a pediatric patient with wound botulism and highlight the
diagnostic and therapeutic difficulties in a setting with limited
access to confirmatory tests and botulinum antitoxin.
Case
presentation: a 12-year-old male with an open, contaminated
fracture of the left tibia and fibula. The clinical presentation
was characterized by dysphagia, dysarthria, and progression
to symmetrical descending flaccid paralysis, accompanied by
cranial nerve involvement, mydriasis, and respiratory failure,
yet with preserved consciousness. Mechanical ventilation was
required. Botulism was suspected retrospectively based on
the clinical course following the fracture. The patient showed
slow but progressive neurological recovery with intensive
support and physical rehabilitation.
Conclusions: wound
botulism should be considered in patients with contaminated
wounds and progressive acute flaccid paralysis.
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