Jiménez GCY, González PN, Villafuerte TG, López CL, Coronado PIA, Gómez FLA

Language: Spanish
References: 11
Page: 281-285
PDF size: 669.55 Kb.

ABSTRACT

Introduction: cerebrovascular autoregulation (CVA) protects the brain from inappropriate variations in cerebral blood flow despite large changes in mean arterial pressure. Loss of CVA is associated with a poor prognosis in critical illnesses. Material and methods: an observational, prospective, longitudinal, comparative study that calculated the individual cumulative survival probability over 90 days using the Kaplan-Meier method in neurocritical and non-neurological critically ill patients with intact or lost CVA. Significant differences in survival were identified between groups using the Log-Rank test. Results: 13 neurocritical patients and 27 non-neurological critically ill patients were recruited. For the first group, survival among those with intact CVA was 80 versus 62.5% for those with lost CVA; for the second group, survival among those with intact CVA was 75 versus 40% for those with lost CVA (p = 0.026). Conclusion: survival is higher when the CVA remains intact, regardless of whether the patient is neurocritical or non-neurologically critical.

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