Nina VCO, Argüero SR, Careaga RG

Language: Spanish
References: 16
Page: 125-135
PDF size: 133.05 Kb.

ABSTRACT

Introduction: Cardiopulmonary bypass has been found to be associated with a wide variety of early posoperative physiologic and immunologic derangements, with a wide spectrum of severity. Objective: To determine if the cardiopulmonary bypass with tepid hypothermia (33-35 °C) offers better protection against the adverse systemic effects of the cardiopulmonary bypass, regarding the moderate (32.9-28 °C). Material and methods: Design: Study of cases and controls, prospective and longitudinal. The patients with diagnose of coronary artery disease with surgical indication were divided according to the systemic temperature of the CPB in two groups, one of tepid hypothermia and another of moderate, in both it was valuated the pulmonary, neurological, haematological and renal complications, clinically and serial laboratorial measurements. Results: The variables with statistical significance at 72 hours were TP p = 0.003, TPTa p = 0.033, INR p = 0.010, transfusion requirements of red blood cells package at 6 hours p = 0.038, time of extubation p = 0.014. Three patients of the group 2 presented minor neurological events. There was not mortality in none of the two groups. Conclusion: The coronary artery bypass grafting surgery with tepid cardiopulmonary bypass requires of smaller volume of red blood cells package in the immediate posoperative, presents smaller affection of the system of coagulation, and better and quicker recovery to normal values, the time of orotraqueal extubation is earlier.

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