Pérez MMG

Language: Spanish
References: 8
Page: 218-220
PDF size: 143.33 Kb.

ABSTRACT

A case of congenital encephallitis by cytomegalovirus is reported. The infection by cytomegalovirus has a high incidence in the first years of life; it usually has a subclinic evolution. When the infection occurs in the first half of pregnancy, the fetus suffers severe injury, because of cytopatic effects in brain tissue; with characteristical features of encephallitis. Principal symptoms are: microcephally, optic atrophy, deafness, cortical brain atrophy, mental retardation, seizures and brain calcifications, microphtalmy.

REFERENCES

1. Remington, Klein. Infectous diseases of the fetus and new born infant. Fourth Ed. Philadelphia: Saunders Company 1995.

2. Stagno S, Pass RF, Cloud G et al. Primary cytomegalovirus infection in pregnancy; incidence, transmission to fetus and clinical outcome. JAMA 1986; 256: 175-8.

3. Stuart A. MD. Molecular epidemiology of cytomegalovirus: Viral transmission among children attending a day care center, their parents, and caretakers. J Pediatr 1988;336:372-77.

4. Kumate J, Gutiérrez G, Muñoz O. Manual de Infectología clínica, 14ava Ed, México, D.F.: Mendez Cervantes, 1994.

5. Pass R. Stagno BJ, Alford C. Specific cell mediated immunity and the natural history of congenital infection with cytomegalovirus. J infect Dis 1983; 148: 953-61.

6. Martha D Yow. Congenital cytomegalovirus disease: A now problem. J Infect Dis 1989; 159: 85-9.

7. Gail JD, Gregory JB. Detection of cytomegalovirus in urine from newborn by using polymerase chain reaction DNA amplification. J Infect Dis 1987; 158: 202-6.

8. Goodman and Gilman. Bases farmacológicas de la terapéutica 9a. ed. México, D.F.: Interamericana, 1996.