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Revista Mexicana de Coloproctología Enfermedades del Ano, Recto y Colon

Revista Mexicana de Coloproctología Enfermedades del Ano, Recto y Colon
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2008, Number 2

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Rev Mex Coloproctol 2008; 14 (2)

Smoking and colorectal cancer

Amarillo HA, Fourcans S, Katsini BR, Manson RR, Amarillo HR
Full text How to cite this article

Language: Spanish
References: 14
Page: 57-62
PDF size: 109.25 Kb.


Key words:

Smoking, colorectal cancer, risk factors, prevention.

ABSTRACT

Background: Latest reports had related smoking habit with an increased incidence of colorectal cancer. Objective: To evaluate smoking habit in patients with colorectal cancer surgery. Design: Retrospective analysis. Material: 169 patients with colorectal cancer operated between May 2004 and May 2007. Exclusion criteria: benign pathology, extracolonic neoplasia, cancer polyp. Methods: Smoking was analyzed as a risk factor of colorectal cancer. Also were evaluated: age, cigarette/day index, diagnosis, cancer location, tumor TNM stage, type of surgery, hospital staying, immediate postoperative morbidity. Results: 51 patients with colorectal cancer with curative resection were treated. (Exclusion: 151). Incidence of smokers was 29%, with 22 cigarettes/day (5-60) and average age was 63 years (41-77), mostly males (53%). In non-smokers average age was 69.2 years (27-90) and 58% were females. Conclusions: Smoking incidence was low in this series. Although and according to literature, patients were younger in smokers, mainly males. No difference in morbidity and tumoral location was found. Tumoral stage trended to be earlier in smoking patients. Further, larger and epidemiologic studies are needed to support this findings.


REFERENCES

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  4. Información de referencia sobre el cáncer – Prevención y factores de riesgo de cáncer colorrectal – American Cancer Society -02 march 2007- http://www.cancer.org/docroot/lrn/lrn_0.asp http://www.cancer.org/docroot/lrn/lrn_0.asp.

  5. Anderson JC, Attam R et al. Prevalence of colorectal neoplasia in smokers. The American Journal of Gastroenterology 2003; 98: 2777–2783. doi:10.1111/j.1572-0241.2003.08671.x

  6. Epstein J. Smoking an Important Risk Factor for Colorectal Polyps -67th Annual Meeting of the ACG: Abstract 5. Presented Oct. 21, 2002. http://www.medscape.com/viewarticle/443440.

  7. Lieberman DA. Colon cancer risk factors identified in prospective cross-sectional study- veterans affairs Medical Center in Portland, Oregon. JAMA 2003; 290: 2959-2967.

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  9. Lee et al. Cigarettes, alcohol, coffee, and caffeine as risk factors for colorectal adenomatous polyps. Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032. Ann Epidemiol 1993; 3: 239-44.

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  11. Zisman AL, Nickolov MAA, Brand RE, Gorchow A, Roy HK. Associations between the age at diagnosis and location of colorectal cancer and the use of alcohol and tobacco. Arch Intern Med 2006; 166: 629-634. http://archinte.ama-assn.org/cgi/content/full/166/6/629

  12. Wong HP et al. Nicotine promotes colon tumor growth and angiogenesis through beta-adrenergic activation- Department of Pharmacology, The University of Hong Kong, China. Toxicol Sci 2007; 97: 279-87. Epub 2007 Mar 16.

  13. Vachani C. RN, MSN, AOCN-Affiliation: The Abramson Cancer Center of the University of Pennsylvania - última vez modificado: 9 de marzo del 2007 http://es.oncolink.org/types/article.cfm?c=5&id=7336&s=11&ss=81

  14. American College of Gastroenterology 67th Annual Scientific Meeting http://www.medscape.com/viewarticle/443440




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Rev Mex Coloproctol. 2008;14