Reséndiz-Colosia JA, Medrano-Ortiz de ZME, Alvarado-Cabrero I, Hernández-San Juan M, Gallegos-Hernández JF, Rodríguez-Cuevas SA

Language: Spanish
References: 12
Page: 165-169
PDF size: 253.53 Kb.

ABSTRACT

Objective: To analyze our experience with a patient subjected to parathyroid carcinoma resection with persistently elevated post-operative parathyroid hormone levels and normocalcemia.
Setting: Tertiary-level healthcare hospital.
Design: Case report.
Case report: Female 44 years of age with initial diagnosis of mediastinal tumor. The patient had antecedents of uretheral lithiasis and renal insufficiency. Detection of severe hypercalcemia and parathyroid hormone elevation suggested hyperparathyroidism. We performed tumoral resection by cervicotomy without complications. During the post-operative period, the patient has exhibited rapid descent in serum calcium levels and has persisted with normal serum calcium for 2 years. At 6 months of surgery, parathyroid hormone values had reduced considerably, but remained high in relation to reference values. The patient was maintained under surveillance and after 18 months parathyroid hormone values reduced gradually until reaching almost normal values.
Discussion: High-level parathyroid hormone during the post-operative period should not be confused with persistent disease while serum calcium levels are normal. In the majority of cases, high post-operative parathyroid hormone levels do not indicate a surgical failure. It is advisable for these patients to remain under long-term surveillance.

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