medigraphic.com
SPANISH

Medicina Interna de México

Colegio de Medicina Interna de México.
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2008, Number 1

<< Back Next >>

Med Int Mex 2008; 24 (1)

Hypopotassemia in hospitalized patients

Macías GEE, García FLFR
Full text How to cite this article

Language: Spanish
References: 11
Page: 3-7
PDF size: 114.80 Kb.


Key words:

hypokalemia, hydroelectrolitic disorders, hospitalary hypokalemia.

ABSTRACT

Background: This hydroelectrolitic disorder with potassium plasmatic levels lower than 3.5 mEq/L has both high incidence and frequency within hospitalized patients, who had higher risk of cardiac, arterial, cerebral vascular and renal disorders.
Objectives: To establish hypokalemia frequency in Hospital Angeles del Pedregal patients, and its most frequent causes and clinical manifestations alike.
Patients and methods: Prospective, longitudinal and observational study at Hospital Angeles del Pedregal since November 1 2006 to February 28 2007. Every patient with serum potassium level lower than 3.5 mE/L when admitted was included, excluding those admitted in pediatrics, gynecology and ambulatory surgery departments. Personal information, potassium serum level (selective membrane potentiometry), hypokalemia clinical signs, possible causes, medicines prescribed before and during hospitalization, and, if any, electrocardiographic study were collected.
Results: 186 out of 3,937 patients had hypokalemia (3.9%): 102 women (54.8%) and 84 men (45.1%), with an average age of 53.6 years (15-95). 52.1% asymptomatic. Most frequent symptom was weakness (75 patients, 40.3%). Most frequent causes were medicine usage (97 patients, 52.1%), and gastrointestinal loss (77, 41.3%), nine patients had no clear cause (4.8%). Sixty-six had electrocardiographic study (35.4%) and only 29 (42.4%) had no hypokalemic alteration. Most frequent electrocardiographic disorder was flat T waves (34.8% of hypokalemic patients).
Conclusions: Hypokalemia is a highly frequent disease at Hospital Angeles del Pedregal (mostly in women older than 50 years), main symptom was muscular weakness and most frequent cause was medicines administration (primarily steroids), diarrhea and flattening of T wave must be specially looked after.


REFERENCES

  1. Gary S, Barry B. Fluid and electrolyte disturbances. En: Harrison´s Principles of Internal Medicine. 16th ed. New York: McGraw-Hill, 2005.

  2. Schaefer TJ, Wolford RW. Disorders of potassium. Emerg Med Clin N Am 2005;23(3):723-47.

  3. Tierney LM. Trastornos de líquidos y electrólitos. En: Diagnóstico clínico y tratamiento. 37ª ed. México: El Manual Moderno, 2002.

  4. García-Frade LF. Hiponatremia en hospitalización. Med Int Mex 2003;19(6):352-5.

  5. Paice BJ, Paterson KR, Onyanga-Omara F, et al. Record linkage study of hypokalaemia in hospitalized patients. Postgrad Med J 1986;62(725):187-91.

  6. Gennari FJ. Hypokalemia. N Engl J Med 1998;339(7):451-7.

  7. Schulman M, Narins RG. Hypokalemia and cardiovascular disease. Am J Cardiol 1990;65:4E-9E.

  8. Smith NL, Lemaitre RN, Heckbert SR, et al. Serum potassium and stroke risk among treated hypertensive adults. Am J Hypertens 2003;16:806-13

  9. Cohen HW, Shantha M, Alderman MH. High and low serum potassium associated with cardiovascular events in diuretictreated patients. J Hypertens 2001;19:1315-23.

  10. Riggs JE. Neurologic manifestations of electrolyte disturbances. Neurol Clin 2002;20:227-39

  11. Webster A, Brady W, Morris F. Recognising signs of danger: ECG changes resulting from an abnormal serum potassium concentration. Emerg Med J 2002;19:74-7.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Med Int Mex. 2008;24