Martínez-Velasco ML ,Espinoza B

Language: Spanish
References: 23
Page: 92-96
PDF size: 156.90 Kb.

ABSTRACT

Several species of trypanosomatids Leishmania, Trypanosoma brucei and Trypanosoma cruzi are human pathogens that present a variety of different mechanisms to cause disease, but have in common the important biology role of surface and secreted proteins. Among the most abundant secreted proteins are proteases, and other molecules that allows them to evade the host immune response. The importance of secreted proteins in these parasites is such, that they have different mechanisms of secretion such as secretion through vesicles or even have a flagellar pocket, organelle whose main function is the exchange of different molecules with the external environment.

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