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2010, Number 1

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Cir Gen 2010; 32 (1)

Transoperative peritoneal lavage with an electrolyzed solution of ionic selectivity in secondary peritonitis

Nachón GFJ, Díaz TJ, Benítez OF, García GF, Santiago GJ, Martínez CAJ

Language: Spanish
References: 30
Page: 11-16
PDF size: 192.30 Kb.


ABSTRACT

Objective: To demonstrate the bactericidal and modulating efficacy of the systemic inflammatory response that results from using an electrolyzed solution of ionic selectivity (ESIS) for the transoperative peritoneal lavage (TOPL) as compared to TOPL with normal 0.9% saline solution (NSS).
Setting: Health Sciences Institute, Universidad Veracruzana, Xalapa, State of Veracruz, Mexico.
Design: Controlled clinical study.
Statistical analysis: Analysis of variance with repeated measures (ANOVA).
Patients and methods: Twelve consecutive patients with sepsis secondary to generalized peritonitis, with similar hemodynamic and antibiotic management, and who required TOPL, randomly assigned to two groups; in one the ESIS was used and in the other the NSS. As variables, we compared the clinical criteria integrating the systemic inflammatory response syndrome (SIRS; cardiac frequency, temperature, respiratory frequency, and the total amount of leukocytes in peripheral blood), the days of in-hospital stay, the need for re-interventions, and mortality.
Results: Significant differences were found in favor of the group in which ESIS lavage was used to control the clinical parameters integrating the SIRS between groups (p ‹ 0.05) starting at 24 h of the surgical treatment. Likewise, the average in-hospital stay (p ‹ 0.04) and the number of reinterventions to control de septic process were more favorable for the ESIS group.
Conclusion: Treatment with ESIS is more effective, since patients present a faster recovery and with a lower index of complications.


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