Flores-Carreras Ó, González-Ruiz MI, Martínez-Espinoza CJ, Calderón-Lara SA

Language: Spanish
References: 8
Page: 275-280
PDF size: 473.79 Kb.

ABSTRACT

Background: Interstitial cystitis is a disease of unknown origin; in the last twenty years several epidemiological studies reported an increase in frequency.
Objective: To describe the symptoms, cystoscopic and histologic findings of 18 cases of interstitial cystitis.
Patients and method: A descriptive, retrospective and analytical study of 331 women with lower urinary tract symptoms studied in Urodifem de Occidente, (private Urogynecology Clinic), between January 2001 and April 2008. The diagnostic criterion was in agreement with the NIDDK and the Interstitial Cystitis DataBase Study. The statistical analysis was in interval scale means, standard deviations and ranges. Indeed Spearman’s rank correlation coefficient.
Results: The most common symptoms were: urinary frequency (100%) nocturia (94.4%), urgency (72%), pain (66.6%), urgency-incontinence (16.7%). Endoscopic lesions were glomerular in 55% and Hunner ulcers in 44.5%. The severity of quality of life resulted in average of 16.7 ± 2.9 and 15 ± 2, p ‹ 0.001.
Conclusions: Urogynecologists must considerer interstitial cystitis when patients show symptoms of bladder irritability and associate pain with the bladder filling. The association of hematuria accompanied by long-term irritability and pain associated with the desire of urination suggests this disease. Cystoscopy is sufficient to confirm the diagnosis.

REFERENCES

1. Oravisto KJ, Alfthan OS, Jokinen EJ. Interstitial cystitis. Clinical and immunological findings. Scan J Urol Nephrol 1970;4:37-42.

2. Held PJ, Hanno PM, Wein AJ, et al. Epidemiology of interstitial cystitis. In: Hanno PM, Staskin DR, Krane RJ, et al, editors. Interstitial cystitis. New York: Springer-Verlag, 1990;p:29-48.

3. Jones CA, Harris M, Nyberg L. Prevalence of interstitial cystitis in the United States. J Urol 1994;151:423A.

4. Curhan GC, Speizer FE, Hunter DJ, et al. Epidemiology of interstitial cystitis: a population based study. J Urol 1999;161:549-552.

5. Gillenwater JY, Wein AJ. Summary of the National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases Workshop on Interstitial Cystitis, National Institutes of Health, Bethesda, Maryland, August 28-29, 1987. J Urol 1988;140:203-206.

6. Simon LJ, Landis JR, Tomaszewski JE, Nyberg LM. The interstitial cystitis database (ICDB) study. In: Sant GR, editor. Interstitial cystitis. Philadelphia: Lippincott-Raven, 1992;p:3:17-32.

7. O’Leary MP, Sant GR, Fowler FJ Jr, et al. The interstitial cystitis symptom index and problem index. Urology 1997;49(Suppl. 5A): 58-63.

8. Messing EM. The diagnosis of interstitial cystitis. Urology 1987;29(Suppl. 4):4-7.