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Anales de Otorrinolaringología Mexicana

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2010, Number 2

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Otorrinolaringología 2010; 55 (2)

Overdiagnose of laryngo-pharyngeal reflux as a cause of hoarseness and other disorders of voice

Zubiaur GFM, James P Thomas JP
Full text How to cite this article

Language: Spanish
References: 11
Page: 52-58
PDF size: 866.10 Kb.


Key words:

laryngopharyngeal reflux, hoarseness, laryngology, phonosurgery.

ABSTRACT

Objectives: 1) To determine the percentage of patients seen in a private laryngology clinic with voice related disorders that are previously diagnosed with and treated for laryngopharyngeal reflux (LPR). 2) To determine how many of those patients are found to have disorders other than LPR as a cause for their voice disorder.
Material and method: A retrospective, chart-review analysis of new patients was conducted from January 2005 through December 2007 in a private laryngology clinic setting. Patients with a previous diagnosis of LPR as the cause of hoarseness, with or without anti-reflux treatment were included. Incomplete charts and patients with additional diagnoses besides LPR were excluded. Patient charts were analyzed in search of different variables including main complaint, previous medications and final diagnosis among others.
Results: 784 consecutive charts were reviewed. Inclusion criteria was met in 105 charts. 82% had no improvement or felt worse after previous anti-reflux treatment while 18% had significant or mild improvement, all patients, however, remained with some degree of hoarseness. Final diagnosis was diverse and was divided into structural and functional precipitators, none of the patients had laryngopharyngeal reflux as a final diagnosis and none of them referred worsening of their voice after respective treatment.
Conclusion: LPR has become an over diagnosed entity. With a thorough history, vocal capability testing and physical exam, an accurate diagnosis can be made in the vast majority of cases. LPR is seldom the cause of voice related disorders and should become a diagnosis of exclusion, not of assumption.


REFERENCES

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  2. Koufman JA. The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. Laryngoscope 1991;101(S53):1-78.

  3. Belafsky P, Postma G, Koufman J. Validity and reliability of the reflux symptom index (RSI). J Voice 2002;16(2):274-277.

  4. Belafsky P, Postma G, Koufman J. The validity and reliability of the reflux finding score (RFS). Laryngoscope 2001;111(8):1313-1317.

  5. Koufman JA, Aviv JE, Casiano RR, et al. Laryngopharyngeal reflux: Position statement of the committee on speech, voice, and swallowing disorders of the American Academy of Otolaryngology-Head and Neck Surgery. Otolaryngol Head Neck Surg 2002;127(1):32-35.

  6. Koufman JA, Amin MR, Panetti M. Prevalence of reflux in 113 consecutive patients with laryngeal and voice disorders. Otolaryngol Head Neck Surg 2000;123(4):385-388.

  7. Merati AL, Lim HJ, Ulualp OS, et al. Meta-analysis of upper probe measurements in normal subjects and patients with laryngopharyngeal reflux. Ann Otol Rhinol Laryngol 2005;114(3):177-182.

  8. Ulualp SO, Roland PS, Toohill RJ, et al. Prevalence of gastroesophagopharyngeal acid reflux events: an evidence-based systematic review. Am J Otolaryngol Head Neck Surg 2005;26:239-244.

  9. Joniau S, Bradshaw A, Esterman A, et al. Reflux and laryngitis: A systematic review. Otolaryngol Head Neck Surg 2007;(136):686-692.

  10. Hopkins C, Yousaf U, Pedersen M. Acid ref lux treatment for hoarseness. Cochrane Database Syst Rev 2006;(25):(1):CD005054.

  11. Vaezi MF. Review article: the role of pH monitoring in extraoesophageal gastro-esophageal reflux disease. Aliment Pharmacol Ther 2006;(23):40-49.




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Otorrinolaringología. 2010;55