2010, Number 1
Rev Mex Urol 2010; 70 (1)
Castillo-de Lira HH, Venegas-Ocampo PJ, Robles-Scott MA, Gutiérrez-Ochoa J, Landa-Soler M, Xochipiltécatl-Muñoz JD
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ABSTRACTObjective: To evaluate cryotherapy as a safe and valid treatment alternative equivalent to radical prostatectomy in localized prostate cancer management.
Materials and methods: A clinical retrospective study was carried out in which 60 case records from the years 2006-2009 of patients diagnosed with localized prostate cancer who underwent cryotherapy (30 patients) or radical prostatectomy (30 patients) were reviewed. The following variables were analyzed: age, Gleason grade, clinical stage, prostate volume, prostate specific antigen (PSA) levels, surgery duration, bleeding, hospital stay and complications.
Results: In the cryotherapy group, surgery duration was a mean 3.5 hours, bleeding was between 30-100 mL with a mean 51 mL and hospital stay was a mean 4.13 days. In the radical prostatectomy group, surgery duration was 3.90 hours, bleeding was from 800-12,500 mL with a mean 2680 mL and hospital stay was a mean 5.07 days. Complications presented in 100% of patients that underwent cryotherapy, the most frequent of which was perineal ecchymosis. In the radical prostatectomy group complications presented in 30% of patients.
Conclusions: The advantages of cryotherapy over radical prostatectomy are reduced blood loss and less serious complications during and after the procedure. Adequate patient selection is necessary for both procedures in order to choose the most appropriate and effective treatment and consequently obtain better results for each patient.