Silva LLM, Torres RH, Ríos RN, Tenorio FE

Language: Spanish
References: 12
Page: 150-156
PDF size: 207.51 Kb.

ABSTRACT

Introduction: In Mexico, breast cancer is the leading cause of death due to cancer in women and is the second leading cause of death overall between 30 and 54 years of age. Mammography is the preferred image method for early detection in women over 40 and calcifications are the most common radiological finding. Most cases are of benign origin, but they may be the first manifestation of early stage cancer. LaFontan, LeGal and Nishimura have identified statistically significant characteristics that support a suspicion of cancer.
Material and methods: A retrospective, longitudinal and descriptive study of markings due to BI-RADS category 4 calcifications, made by mammography at the Hospital General de Mexico Mammary Imaging Department from September 1, 2010, through October 31, 2011. Histopathological results, localization by quadrant, type of marking, post-operative control, and BI-RADS and LeGal classification of the type of calcifications and their distribution were obtained.
Results: Fifty-six markings were made, of which 10 were excluded because they lacked histopathological reports, 5 patients presented bilateral lesions. The calcifications were associated with asymmetries, nodules, and distortions in architecture in only 5 cases. The upper quadrants were the most affected, with predominance on the left side (54%). The most common types of calcifications were pleomorphic and punctiform, distributed mainly in clusters. Based on the LeGal classification, 20 type 4 cases were found, 14 type 3, 11 type 2, and 1 type 5. Of the excisional biopsies 72% corresponded to benign pathology and histopathological indications of malignancy were found in only 28%.
Conclusions: The quality of mammography and the radiologist’s experience influence the classification of calcifications. Despite their radiological appearance, only 28% of the BIRADS category 4 calcifications corresponded to carcinomas. A close correlation needs to be made with the clinical and histopathological antecedents.

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