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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2012, Number 08

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Ginecol Obstet Mex 2012; 80 (08)

Assisted Hatching Following Embryo Implantation Failure

Carballo ME, Durán ML, Campos CJA, González JP, Kably AA
Full text How to cite this article

Language: Spanish
References: 9
Page: 509-513
PDF size: 78.77 Kb.


Key words:

Assisted hatching, implantation failure, assisted reproduction.

ABSTRACT

Background: Assisted hatching in reproduction techniques has improved the successful implantation rates in certain groups of patients with poor prognosis. This study focuses on its effect in groups of patients with previous implantation failure and according to age groups.
Objective: Compare the pregnancy rates of patients who turned to this technique following an implantation failure using in vitro fertilization with those of patients who did not use assisted hatching before another attempt of in vitro fertilization and according to specific age groups.
Material and method: Cases of patients using assisted hatching in our Center between January 2008 and December 2009 were studied. The results were compared in terms of age in three groups: group I, ›35 years; group II, 35-39 years, and group III, › 40 years.
Results: Patients in group II had better pregnancy rate (30%) than those in groups I and III (16.98 and 20.83%, respectively). When comparing the results of the group of patients using assisted hatching with those of the group that did not, the first reported a 20% pregnancy rate versus no pregnancy in the other group.


REFERENCES

  1. Balaban B, Urman B, Alatas C, Mercan R, Mumcu A, Isiklar A. A comparison of four different techniques of assisted hatching. Hum Reprod 2002;17(5):1239-1243.

  2. Das S, Blake D, Farquhar C, Seif MM. Assisted hatching on assisted conception (IVF and ICSI). Cochrane Database Syst Rev 2006;(1):CD001894.

  3. Ebner T, Shebl O, Mayer RB, Tews G. Relevance of the site of assisted hatching in thawed human blastocysts. Fertil Steril 2010;94(4):e65-66.

  4. Ge HS, Zhou W, Zhang W, Lin JJ. Impact of assisted hatching on fresh and frozen-thawed embryo transfer cycles: a prospective, randomized study. Reprod Biomed Online 2008;16(4):589-596.

  5. Ciray N, Bener F, Karagenc L, Ulug U, Bahceci M. Impact of assisted hatching on ART outcome in women with endometriosis. Hum Reprod 2005;20(9):2546-2549.

  6. Sifer C, Sellami A, Poncelet C, Kulski P, Martin-Pont B, Bottero J, et al. A prospective randomized study to assess the benefit of partial zona pellucida digestion before frozen-thawed embryo transfers. Hum Reprod 2006;21(9):2384-2389.

  7. Hiraoka K, Fuchiwaki M, Hiraoka K, Horiuchi T, Murakami T, Kinutani M, Kinutani K. Effect of the size of zona pellucida opening by laser assisted hatching on clinical outcome of frozen cleaved embryos that were cultured to blastocyst after thawing in women with multiple implantation failures of embryo transfer: a retrospective study. J Assist Reprod Genet 2008;25(4):129-135.

  8. Hagemann AR, Lanzendorf SE, Jungheim ES, Chang AS, Ratts VS, Odem RR. A prospective, randomized, doubleblinded study of assisted hatching in women younger than 38 years undergoing in vitro fertilization. Fertil Steril 2010;1-7.

  9. De Moraes LA, de Miranda Cota AM. Assisted hatching improves implantation rates on cryopreserved-thawed embryos. A randomized prospective study. Hum Reprod 2005;20(5):1429 -1430.




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Ginecol Obstet Mex. 2012;80