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2012, Number 4

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Med Crit 2012; 26 (4)

3rd. place Winner to Prize «Dr. Mario Shapiro»
Colloidosmotic pressure (COP) as a prognostic indicator in trauma. Preliminary report

Basilio OA, Briones JC, Jiménez OJA, Díaz LPMA
Full text How to cite this article

Language: Spanish
References: 8
Page: 230-233
PDF size: 60.94 Kb.


Key words:

Trauma, colloidosmotic pressure (COP), hemorraghe, Landis-Pappenheimer.

ABSTRACT

Introduction: Colloidosmotic pressure (COP) is force exerted by the protein on the capillary membranes. Starling demonstrated the importance of this pressure to establish a pressure gradient between the interstitial and capillary space wich prevents capillary leakage into the interstitial space. We used the formula 1 of Landis-Pappenheimer to determine the state of the capillary in presence of bleeding.
Material and methods: In this report, we applied the formula 1 of Landis-Pappenheimer to 25 patients admitted to the Central Hospital of the Mexican Red Cross, with a history of severe trauma, all bleed 2,000 mL or more, between 1° March at 31 May 2012 and were subjected to 1 or more surgeries.
Results: Of the 25 Injury, the main cause was the car accident in 7 cases, males prevailed in 84%, the average bleeding was 2.7 liter per patient, the small bowel was the organ most affected, the PCO for survivors was 18.7 torr and 107 in deaths.
Conclusions: The present study although a preliminary report is the first worldwide wich is the measurement of PCO may be useful in predicting the risk of death in the trauma patient a fact that has been shown by other authors in our country.


REFERENCES

  1. Díaz de León PM, Herrera RC, Cruz LC. Valor normal de la presión coloidosmótica en adultos sanos de la Ciudad de México. Arch Invest Med (Mex) 1981;12:307-321.

  2. Feliciano D, Mattox K, Moore D. Trauma management of shock. 6th Edition. Ed. Interamericana 13:715-60.

  3. Nematbakhsh M, Moradi A. Mathematical model for determination of colloidosmotic pressure. J Res Med Sci 2006;6:364-9.

  4. Díaz de León PM, Reyes NV, Sánchez VEC, Cruz LC. La presión coloidosmótica como índice de supervivencia. Rev Asoc Mex Med Crit Ter Int 1987;3:11-4.

  5. Landis EM, Pappenheimer JR. Exchanges of substances through the capillary walls. Handbook of physiology. Circulation Physiol Soc Washington DC. Set. 2 Chapt 29.

  6. Briones GJC, Díaz de León PM, Gómez BTE, Ávila TEF, Ochoa RC, et al. Medición de la fuga capilar en la preeclampsia-eclampsia. Cir Ciruj 2000;68:194-7.

  7. Peitzman A, Corbett WA, Shires GT. Cellular function in liver, and muscle during hemorrhagic shock in primates. Surg Gynecol Obstet 1985;161:419-27.

  8. Programa Vital de Apoyo Avanzado para Médicos. Editado por el Colegio Americano de Cirujanos. Comité de Trauma. 7a Edición 2007:73-106.




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C?MO CITAR (Vancouver)

Med Crit. 2012;26