Ortiz LJB, Vallarta RRA, Lavenant BMI, Esquivel CVA

Language: Spanish
References: 9
Page: 11-16
PDF size: 331.51 Kb.

ABSTRACT

The Gelfoam® or Spongostan® gelatin sponge is a water-insoluble and porous haemostatic medical material that has been used for more than 70 years. Some surgeons use it in rhinoplasties for cartilage graft stability on nasal dorsum. Some articles favour the use of this biomaterial as a cartilage matrix with apparent maintenance of cartilage viability; however, there is no histological supporting evidence. We carried out a prospective and comparative experimental study between four cartilage sample groups associated with Spongostan®, taken eight weeks after subcutaneous implantation in Wistar rats to describe and compare six histological characteristics decisive in cartilage feasibility. We evidenced a loose fibroblastic response in the Spongostan® and cartilage sample 2.42 times higher versus isolate cartilage and 2.17 times higher versus isolated gelatin sponge, 100% cartilage feasibility and cartilage neoformation 10.31 times lower compared to the isolated cartilage. This biomaterial related to the cartilage graft allows: no graft movement, cartilage feasibility maintenance, complete gelatin sponge absorption and maintenance of «controlled» condrocite differentiation.

REFERENCES

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