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ISSN 1561-3119 (Electronic)

2013, Number 2

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Rev Cubana Pediatr 2013; 85 (2)

First case of C1q nephropathy in Cuba

Campañá CNG, Chong LA, Durán ÁS, Hernández HS, Valdés MM

Language: Spanish
References: 14
Page: 258-264
PDF size: 236.03 Kb.


ABSTRACT

C1q nephropathy is a poorly understood glomerulopathy with some conceptual controversies, but with a distinctive immunologic characteristic (dominant or co-dominant deposit of C1q) and neither clinical nor serological evidence of systemic erythematous lupus. This is the case of a male patient who began suffering nephritic syndrome with hematuria, blood hypertension and renal failure at 10 months of age. A first renal biopsy was performed to detect diffuse mesangeal sclerosis; however after partial response of the patient to prednisone therapy and to maintenance treatment of proteinuria in nephritic range, with normalization of humoral parameters, then a second renal biopsy was performed with immunofluorescence. The final result was C1q nephropathy.


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