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Academia Mexicana de Neurología, A.C.

2013, Number 2

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Rev Mex Neuroci 2013; 14 (2)

Hashimoto encephalopathy: A case report

Posadas-Zúńiga G, Palafox-Vigil G, García-Esquivel MA

Language: Spanish
References: 24
Page: 86-88
PDF size: 884.90 Kb.


ABSTRACT

Hashimoto’s encephalopathy was first described in 1966, since then, the literature shows a female-male ratio of presentation of 4:1. In the present article we report a case of a male aged 53 years with no relevant medical history, who began with cognitive impairment and generalized tonic clonic seizures at admission, with Folstein minimental test score of 22/30 points. Laboratories were requested to report anti-thyroglobulin antibodies 1:168, antimicrosomal 1:550.9. The EEG reported decrease in theta waves. The contrast-enhance magnetic resonance imaging did not show enhancement in any brain area. The diagnosis of Hashimoto encephalopathy was formulated. The corticosteroids treatment resolved the clinical and cognitive function.


REFERENCES

  1. Vernino S, Geschwind M, Boeve B. Autoimmune encephalopathies. Neurologist 2007; 13: 140-7.

  2. Su TH, Jin EH, He W. Hashimoto encephalopathy: a case report with proton MR spectroscopic findings. Chin Med J (Engl) 2011; 124: 3420-2.

  3. Chong CS, Leung JL, Wong IH, Ng PW, Miao MY. Presenile dementia: a case of Hashimoto’s encephalopathy. East Asian Arch Psychiatry 2011; 21: 32-6.

  4. Zhao W, Li J, Wang J, Guo Y, Tuo H, Kang Z, Jiang B, Wang R, Wang D. A case of Hashimoto encephalopathy: clinical manifestation, imaging, pathology, treatment, and prognosis. Neurologist 2011; 17: 141-3.

  5. Lee SW, Donlon S, Caplan JP. Steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT) or Hashimoto’s encephalopathy: a case and review. Psychosomatics 2011; 52: 99-108.

  6. Ferracci F, Bertiato G, Moretto G. Hashimoto’s encephalopathy: epidemiologic data and pathogenetic considerations. J Neurol Sci 2004; 217: 165-8.

  7. Sporis D, Habek M, Mubrin Z, Poljaković Z, Hajnsek S, Bence-Zigman Z. Psychosis and EEG abnormalities as manifestations of Hashimoto encephalopathy. Cogn Behav Neurol 2007; 20: 138-40.

  8. Leyhe T, Morawetz C, Zank M, Buchkremer G, Eschweiler G. Epilepsy in an elderly patient caused by Hashimoto’s encephalopathy. Epileptic Disord 2007; 9: 337-40.

  9. Singh K, Kashyap S. Hashimoto’s encephalopathy. The Lancet 2003; 361: 1912.

  10. Aquino RT, Mutarelli EG. Hashimoto’s encephalopathy. Arq Neuropsiquiatr 2009; 67: 724-5.

  11. Grommes C, Griffin C, Downes KA, Lerner AJ. Steroid-responsive encephalopathy associated with autoimmune thyroiditis presenting with diffusion MR imaging changes. AJNR Am J Neuroradiol 2008; 29: 1550-1.

  12. Tzakas P, Sit SW. Progressive impairment of cognition and motor function: Hashimoto encephalopathy. CMAJ 2011; 17; 183: E495-7.

  13. Vernino S, Geschwind M, Boeve B. Autoimmune encephalopathies. Neurologist 2007; 13: 140-7.

  14. Su TH, Jin EH, He W. Hashimoto encephalopathy: a case report with proton MR spectroscopic findings. Chin Med J (Engl) 2011; 124: 3420-2.

  15. Chong CS, Leung JL, Wong IH, Ng PW, Miao MY. Presenile dementia: a case of Hashimoto’s encephalopathy. East Asian Arch Psychiatry 2011; 21: 32-6.

  16. Zhao W, Li J, Wang J, Guo Y, Tuo H, Kang Z, Jiang B, Wang R, Wang D. A case of Hashimoto encephalopathy: clinical manifestation, imaging, pathology, treatment, and prognosis. Neurologist 2011; 17: 141-3.

  17. Lee SW, Donlon S, Caplan JP. Steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT) or Hashimoto’s encephalopathy: a case and review. Psychosomatics 2011; 52: 99-108.

  18. Ferracci F, Bertiato G, Moretto G. Hashimoto’s encephalopathy: epidemiologic data and pathogenetic considerations. J Neurol Sci 2004; 217: 165-8.

  19. Sporis D, Habek M, Mubrin Z, Poljaković Z, Hajnsek S, Bence-Zigman Z. Psychosis and EEG abnormalities as manifestations of Hashimoto encephalopathy. Cogn Behav Neurol 2007; 20: 138-40.

  20. Leyhe T, Morawetz C, Zank M, Buchkremer G, Eschweiler G. Epilepsy in an elderly patient caused by Hashimoto’s encephalopathy. Epileptic Disord 2007; 9: 337-40.

  21. Singh K, Kashyap S. Hashimoto’s encephalopathy. The Lancet 2003; 361: 1912.

  22. Aquino RT, Mutarelli EG. Hashimoto’s encephalopathy. Arq Neuropsiquiatr 2009; 67: 724-5.

  23. Grommes C, Griffin C, Downes KA, Lerner AJ. Steroid-responsive encephalopathy associated with autoimmune thyroiditis presenting with diffusion MR imaging changes. AJNR Am J Neuroradiol 2008; 29: 1550-1.

  24. Tzakas P, Sit SW. Progressive impairment of cognition and motor function: Hashimoto encephalopathy. CMAJ 2011; 17; 183: E495-7.




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