Domínguez-Moreno R, Olán-Triano R, Gutiérrez-Morales JL, Mena-Arceo R, Reyes-de la Cruz A

Language: Spanish
References: 11
Page: 89-93
PDF size: 720.10 Kb.

ABSTRACT

Introduction: Acute disseminated encephalomyelitis is a demyelinating disease of central nervous system with an immunoallergic pathophysiology, usually occurring in young patients, with monophasic course and good prognosis, following an infection or immunization; which occurs with an incidence of 0.4 to 3/100,000 inhabitants per year in those those under 20 years of age. Case Reports: Case 1: a 13-year-old male who starts with acute pharyngitis and fever, nausea and vomiting, with a latter addition of convulsive crises and subsequent quadriparesis, who had discarded neuroinfection, but MRI showed images compatible with typical demyelination. Case 2: a 7-year-old female who after application of triple viral vaccine and influenza develops nausea and vomiting, left hemiparesis and central facial ipsilateral paralysis. Other differential diagnoses were also ruled-out. Brain MRI showed multiple hyperintense lesions compatible with demyelination. Both cases were consistent with the diagnosis of acute disseminated encephalomyelitis and both were treated with corticosteroids, showing a good clinical evolution. Discussion: Although acute disseminated encephalomyelitis is rare, is particularly important due to neurological sequels secondary to inadequate diagnosis and treatment. It should be suspected in the young population with encephalitis and a history of infection or recent vaccination.

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