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Revista de Especialidades Médico-Quirúrgicas

Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
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2013, Number 3

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Rev Esp Med Quir 2013; 18 (3)

Thyroid Disorders and Pregnancy: Perinatal Results

Serrano BMÁ
Full text How to cite this article

Language: Spanish
References: 12
Page: 200-205
PDF size: 314.35 Kb.


Key words:

hyperthyroidism, hypothyroidism, pregnancy.

ABSTRACT

Background: Thyroid disorders rank second among endocrine disorders associated with pregnancy because its incidence is higher in women's reproductive stages.
Objectives: To determine the incidence of the association between thyroid disease and pregnancy.
Material and method: A transverse clinical study was conducted, in which a group of women with thyroid disorders was compared vs a control group. The variables in the study were: maternal age, parity, gestational age at the time of the resolution of the pregnancy, weight products to the birth and Apgar rating. Statistical analysis was performed using Fisher's exact test.
Results: Seventy-two pregnant patients were included: 24 with hyperthyroidism and 48 with hypothyroidism. In the group of patients with hypothyroidism a statistical difference (p‹0.05) was found in abortion and low birth weight compared to the control group, in which a statistical difference was found (p ‹0.05) in the absence of complications associated and pregnancy resolution via vaginal. In the group of women with hyperthyroidism a statistical difference was found (p ‹0.05) in low birth weight compared with the control group, where a statistical difference (p ‹0.05) was observed in the absence of associated maternal complications and pregnancy resolution via vaginal. The remaining variables studied in both groups had no statistically significant difference.
Conclusions: It is required to maintain close monitoring of patients with thyroid disorders to obtain successful perinatal results and avoid complications.


REFERENCES

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  2. Medici M, Timmermans S, Visser W, De Muinck Keizer- Schrama SM, et al. Maternal thyroid hormone parameters during early pregnancy and birth weight: the Generation R Study. J Clin Endocrinol Metab 2013;98:59-66.

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  4. Cignini P, Cafà EV, Giorlandino C, Capriglione S, et al. Thyroid physiology and common diseases in pregnancy: review of literature. J Prenat Med 2012;6:64-71.

  5. Budenhofer BK, Ditsch N, Jeschke U, Gärtner R, et al. Thyroid (dys-)function in normal and disturbed pregnancy. Arch Gynecol Obstet 2013;287:1-7.

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  8. Sarkar D. Recurrent pregnancy loss in patients with thyroid dysfunction. Indian J Endocrinol Metab 2012;16:350-351.

  9. Lepoutre T, Debiève F, Gruson D, Daumerie C. Reduction of miscarriages through universal screening and treatment of thyroid autoimmune diseases. Gynecol Obstet Invest 2012;74:265-273.

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Rev Esp Med Quir. 2013;18