Munguía-Félix AL, Guerrero-Avendaño G

Language: Spanish
References: 13
Page: 216-222
PDF size: 231.17 Kb.

ABSTRACT

Introduction. Nasosinusal non-Hodgkin’s lymphoma is a malignant, lymphoproliferative, extranodal neoplasm, originating B, T, or natural killer cells. Age of onset is primarily the sixth decade of life, with greater predominance in males. Initially the disease is asymptomatic, although patients often report nonspecific symptoms of nasal obstruction and secretion. In descending order, the localization is nasal cavity, maxillary sinus, ethmoid sinus, and frontal sinus. Its radiological appearance in multislice computed tomography (MSCT) is that of a lesion in soft tissue range, of lobulillar or polypoidal aspect, voluminous and uniform, occasionally slightly hyperdense, which remodels, expands, erodes, or destroys bone. Following administration of contrast medium it presents a uniform and moderate highlight.
Material and methods. A longitudinal, retrospective study was conducted, with 33 patients who underwent MSCT at Hospital General de Mexico (HGM) and whose radiological diagnosis was of probable nasosinusal lymphoma; the diagnosis was subsequently confirmed by pathological anatomy. The objective was to prove the customary behavior, by MSCT, of nasosinusal lymphomas and identify their most common localizations in patients who use our hospital. The WHO classification for histopathological staging was used.
Results. Of 33 patients included in the study, 18 were males (54.5%) and 15 females (45.5%). The histological type was lymphoma of natural killer T-cells in 84.8% of patients and of T cells in 15.2%. The localization of origin was the nasal cavity in 93.9% and maxillary sinus in 6.1%. › The most common radiological finding was soft tissue tumor of polypoidal appearance with uniform highlight following administration of intravenous contrast, in addition to bone remodeling , expansion, and destruction.
Discussion. The lymphomas represent the second most common neoplasm in nasosinusal cavities, exceeded only by epidermoid carcinoma. We found that in patients at HGM the most common location was in nasal cavities and its behavior in MSCT is similar to that described in the specialized literature. Findings that differ from those reported differ in terms of histological type and age at onset, given that our patients presented the histological type natural killer T-cells and the most common age was the fourth decade of life.
Conclusions. At HGM, as in other series, nasosinusal lymphoma has its most common localization in nasal cavities, and secondly in maxillary sinuses. The radiological appearance coincides with findings reported in the literature; however, because other tumors have the same radiological pattern findings should be histopathologically correlated. In patients at our hospital the most common histological variety was natural killer T lymphocytes and the most common time of onset was in the fourth decade of life.

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