Juárez-Duarte ES, Amezcua-Herrera MC, Zea-Arévalo FD, Guerrero-Avendaño G

Language: Spanish
References: 10
Page: 223-230
PDF size: 958.52 Kb.

ABSTRACT

Introduction. Human adjuvant disease induced by foreign substances is an entity which first appeared in 1899 in association with the use of testicular prosthetics; there was a significant increase in the use of modeling substances between 1950 and 1970, using paraffin and later liquid silicone. The term human adjuvant disease induced by foreign substances was coined by Miyoshi in 1972 in patients with breast implants. In Mexico the first cases were reported in the 1970s. Today human adjuvant disease induced by foreign substances is a serious public health problem.
Material and methods. Thirty patients diagnosed with human adjuvant disease induced by foreign substances were attended at the Hospital General de Mexico Radiology and Image Service between 2010 and 2013 were used. A Carestream Picture Archiving Communication System (PACS) version 11.0 hgm and Siemens 1.5 tesla Magneton Avanto model resonator were used.
Results. Mineral oil was the most commonly used modeling agent. The most impure substances, such as industrial oils, have a much earlier presentation period and more aggressive clinical manifestation than more inert substances like silicone. The upper external quadrants were the most commonly affected zone. The spread of infiltration occurred most commonly in fat of the ischiorectal fossa. Mineral oil showed a predilection for affecting the upper external quadrants, spreading to the ischiorectal fossa, and infiltration to the gluteus maximus muscles.
Discussion. The results of our study are consistent with results from prior studies, where there is a clear relationship between time of onset of symptoms, severity and extent of infiltration, and type of substances used: inert or impure. There is limited information on the relationship between the type of modeling agent and its areas of infiltration.
Conclusion. Inert substances are much more aggressive. The upper external quadrants and the ischiorectal fossa are the most commonly affected sites. Human adjuvant disease induced by foreign substances is a serious public health problem, but notwithstanding is a poorly evaluated disorder due to the scant information on its physical, psychological, and socioeconomic effects, among both physicians and their patients.

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