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2013, Number 4

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Rev Esp Med Quir 2013; 18 (4)

Efficacy of Oral Anticoagulant Treatment and Incidence of Complications in Anticoagulant Clinic

López LM, López PM, Vidales LA
Full text How to cite this article

Language: Spanish
References: 14
Page: 292-298
PDF size: 362.98 Kb.


Key words:

anticoagulant therapy, current anticoagulant efficacy, INR grades, sub-anticoagulated, optimal, over-anticoagulated, anticoagulant clinic complications.

ABSTRACT

Background: Anticoagulant therapy is more frequent by the growing number of heart surgeries and thrombus embolic problems. Control and surveillance is needed in order to avoid life threatening complications. The INR is the test to control. INR optimum values are 2.00 to 3.5, suboptimal value is below 2.00 and implies risk of thromboembolism, and anticoagulated (above 3.5) implies risk of bleeding.
Objective: To determine the efficacy of anti-coagulation in patients in control, as well as the incidence of complications.
Material and method: Retrospective and descriptive study of 40 patients, of whom 23 were finally chosen. We analyzed the INR results obtained over a year. The effectiveness was assessed based on the INR as: optimum, anticoagulation, and subanticoagulacion, as well as in the absence of complications. The variables considered were: age, degree of INR, co-morbidity and complications suffered in a year.
Results: In order to analyze the effectiveness of anticoagulation, we evaluated regular patients (23 of 40), 52.5% of them were masculine and 47.5% were feminine, with a range of 37 to 85 years old and an average of 61 years. A 90% of them were older than 50 years; in total, 60% of the patients were older than 60 years. Co-morbidities found were diabetes and hypertension (57%) and a history of surgery (57%).
Conclusion: Efficacy of anticoagulant intensity in optimal therapeutic range was 70%. A 23.5% of the patients were in sub-anticoagulated level and 6.37% were in over-anticoagulated level. Were observed complications in 2.5% of patients; 97.5% of them had no complications while 30% had values that were outside the optimal range during 2012. The complications observed in the anticoagulation clinic along 9 years are 10% (four patients).


REFERENCES

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Rev Esp Med Quir. 2013;18