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Colegio de Medicos y Cirujanos República de Costa Rica

2013, Number 608

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Rev Med Cos Cen 2013; 70 (608)

Miastenia gravis

Gamboa AMA

Language: Spanish
References: 13
Page: 649-654
PDF size: 196.22 Kb.


ABSTRACT

Myasthenia gravis is an autoimmune dissease caused by antibodies to the acetylcholine receptor (AChR) at the post-synaptic site of the neuromuscular junction. The symptoms of myasthenia gravis may include eye muscle weakness, ptosis, diplopía, a change in facial expression, difficulty in swallowing, shortness of breath.Laboratory confirmation of the clinical diagnosis may be obtained using pharmacological, electrophysiological, and serological (immunological) tests.Medical treatment for myasthenia gravis involves the use of anticholinesterase agents, immunosuppressive drugs, plasmapheresis, and gammaglobulin. Thymectomy has become increasingly accepted as an efficacious procedure for myasthenia gravis.


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