2011, Number 27
Hipoc Rev Med 2011; 6 (27)
Empleo de un Cono de Material Orgánico vs Inorgánico en la Reparación de un Defecto Herniario en un Modelo Animal
Ramos-Gallardo GO, Rodríguez-Madrigal R, González-Reynoso LI, Orlando-Busch R
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ABSTRACT
Introduction: Know the resistance, security and usefulness of organic mesh (bovine pericardium) in the repair of abdominal defects in an animal model.Methods: Twelve, Wistar rats, weights 300 to 500 gr, were anesthetized and a 1 centimeter abdominal defect was created in each animal. Animals were divided according to the repair material: bovine pericardium mesh (n=6) and polipropilene mesh (n=6). Animals were euthanized on 28 days after the surgery. Presence of infection, necrosis and adherences (macroscopic and microscopic) was compared. Tensile force was measured in both groups. Means were compared using the T student test and nominal variables were compared with chi square.
Results: Inflammation, necrosis and adherence formation were similar in both groups. The prolene mesh (mean rupture force 66.5 joules) is stronger than bovine pericardium (mean rupture force 47.4 joules) (p =.002.) The prolene mesh had more adherence than the pericardium cow mesh.
Conclusion: There is no difference in inflammation, necrosis and adherences betweeen the two groups. The polipropilene mesh is stronger than the bovine pericardium mesh. This finding could have relevance in the clinical practice (hernia recurrence) and should be evaluated in future clinical models.
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