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2014, Number 4

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Med Int Mex 2014; 30 (4)

Coinfection with Virus of Hepatitis B or C in Patients Infected by HIV

Segoviano-Mendoza G, Torres-Erazo DS, Tovar-Serrano A
Full text How to cite this article

Language: Spanish
References: 15
Page: 365-372
PDF size: 458.57 Kb.


Key words:

HIV, AIDS, hepatitis C, hepatitis B, co-infection.

ABSTRACT

Background: Hepatitis B and C virus (HBV/HCV) infection in HIVinfected individuals may escape at the immune control and generate chronic illness sometimes hidden.
Objective: To determine the existence of HIV co-infection with HBV or HCV, in patients treated at a private hospital in Mexico City.
Material and method: A cross-sectional study performed from October 2009 to June 2012 included all patients with HIV treated at infectology service of Sanatorium Durango Hospital Center, Mexico City. Were ordered: transaminases, serology for hepatitis A (HAV), HBV and HCV virus, viral loads of hepatitis B, C, HIV and CD4 count. The analysis was performed using SPSS 13.0.
Results: 41 patients were included, 90% (n = 37) were male and 82% (n = 34) were under HAART at the beginning of the evaluation; 32 attended the studies performed; 27 carried out HBV viral load, HCV and HIV, and 29 were submitted to viral hepatitis serology, finding that all had IgG against HAV. Nine patients showed antibodies against the surface antigen (31%) and one had anti-HCV antibodies (3.4%). Viral loads showed only one patient with detectable viremia of HBV and three with detectable viral load of HCV.
Conclusions: Patients living with HIV/AIDS, even though they are on antiretroviral treatment and adequate CD4 count and HIV viral load undetectable, may have active co-infection with HBV and even hidden and/or HCV, by emphasizing the importance of monitoring of that co-infection.


REFERENCES

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Med Int Mex. 2014;30