Jiménez TJP

Language: Spanish
References: 10
Page: 845-847
PDF size: 424.94 Kb.

ABSTRACT

Insulinomas are the most common pancreatic endocrine tumors. These are derived from the beta cells of the pancreatic islets and its incidence is rare. 90% of the cases are solitary, sporadic and benign with location evenly distributed throughout the pancreas. Its diagnosis is associated with the Whipple triad and its associated with an autonomic secretion of insulin which produces a deep fast hypoglycemia with neuroglicopenic symptoms. The both prequirurgical studies are the tomograpic scan and endoscopic ultrasound which can ubicate approximately 100% of tumors. The treatment of choice is surgery which allows to obtain high rates of curation and a better long term survival.

REFERENCES

1. Cryer, P et al Evaluation and management of adult hypoglicemic disorders J Clin Endocrinol Metab, 2009; 94: 709-28

2. Diéguez, M et al Insulinoma: Criterios diagnósticos y tratamiento. Av Diabetol 25: 293-9, 2009

3. Frankel, W. Update on pancreatic endocrine tumors Arch Pathol Lab 2006 130 (7); 963-966

4. Giraldo, J et al Insulinoma del páncreas: reporte de tres casos y discusión Rev Col Gastroenterol 23 (3) 2008

5. Goldin, S et al Sporadically ocurring functional pancreatic endocrine tumors: review of recent literature Curr Opin Oncol 2008 20 (1): 25-33

6. Guetier, J et al Localization of insulinomas to regions of the pancreas by intraarterial calcium stimulation, the NIH experience. J Clin Endocrinol Metab. 2009; 94: 1074- 80

7. Kimberly , A et al Trends in the presentation and management of functioning insulinoma at the Mayo Clinic J Clin Endocrinol Metab. 2009; 94: 1069-1073

8. Klimstra, D et al Pancreatic endocrine tumors; nonfunctioning tumors and microadenomas JARC Press 2004; 201-204

9. Sudhendu, P et al Insulinoma. Case report an review of treatment modalities Journal of the Association of Physicians of India. 2013(61) 423-426

10. Tucker, O et al The management of insulinoma Br J Surg 2006; 93: 264- 5.