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2006, Number 4

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Dermatología Cosmética, Médica y Quirúrgica 2006; 4 (4)

Darier´s Disease: a review

Campos-Fernández MM, Serra E, Alomar A, Dalmau J
Full text How to cite this article

Language: Spanish
References: 32
Page: 261-267
PDF size: 474.02 Kb.


Key words:

Darier’s disease, diskeratosis follicularis, hiperkeratosic papules, acantolisis, oral retinoids.

ABSTRACT

Darier-White disease is a dermatosis that was first reported in 1889, it is transmitted in an autosomic dominant fashion and is characterized by hyperkeratotic papules localized mainly at seborrheic regions as well as ungueal abnormalities. It commonly begins between the first and the second decades of life. Its diagnosis is made by its clinical and histopathological unique features and its treatment is chiefly based on oral retinoids such as isotretinoin. The most important morbidities of Darier disease are the psychosocial consequences of their physical appearance and the chronicity of the disease. Its prevalence varies around the world being more present at some European countries in contrast to Latin-American ones. In Mexico it is a rare condition that is sometimes underdiagnosed; that is our reason for making this revision with the aim of knowing Darier’s more common features in order to make an earlier diagnosis and therefore avoid possible complications and repercussions in the life quality of the patients with Darier’s disease.


REFERENCES

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Dermatología Cosmética, Médica y Quirúrgica. 2006;4