Márquez VS, Villalón FMJ, Escalona LE, Pérez PZ, Alberto PC, Padilla GC

Language: Spanish
References: 8
Page: 610-618
PDF size: 94.81 Kb.

ABSTRACT

Objective: to describe the characteristics of the corneal endothelium in older people living in "Hermanas Giralt" home for the elderly.
Methods: one hundred twenty eyes from 60 old women were studied in a descriptive and cross-sectional study performed from April through September 2013. The patients were examined by biomicroscopy and endothelial microscopy. The images were analyzed and the cellular density, the variability coefficient, the cellular hexagonality and the pachymetry were all evaluated.
Results: the average cell density was 1 926 cel/mm2 in 60-69 years-old patients, which gradually lowered to 1 495 in patients older than 90 years. The variability coefficient increased with age, showing 0,37 for ages 60-69 years and 70-79 years and it was 0,41 in older than 91 years. Hexagonality was higher in 70-79 years-old agroup (49 %) followed by the 80-89 years age group (48 %). In 60-69 years-old (43 %) and in 90 and over age group (30 %), there was a 13 % hexagonality reduction with statistical significance. Cell density, variability coefficient and pachymetry did not show significant differences in relation to age.
Conclusions: the cell density and hexagonality decreased with the age, but variability coefficient and pachymetry increased. The values of corneal endothelium were normal in older adults in our setting.

REFERENCES

1. Charafeddin W. Estudio comparativo entre microscopia confocal y microscopia especular en la valoración del endotelio en córneas con distrofia de Fuchs. Universidad Autónoma de Barcelona; 2011 [citado 26 de enero de 2014]. Disponible en: http://www.recercat.cat/handle/2072/179194

2. Pérez TA. Método de análisis endotelial mediante microscopia especular de no contacto y sistema de análisis por la imagen. Valencia, España: Servicio Oftalmología. Hospital Universitario "La Fe"; 2002.

3. Molina Rey DF, Gómez A. Evaluación por décadas de edad del comportamiento de las células endoteliales corneales en población mexicana. Rev Mex Oftalmol [Internet]. 2005 [citado 26 de enero de 2014];79(2):[aprox 2 p.]. Disponible en: http://www.imbiomed.com.mx/1/1/articulos.php?method=showDetail&id_articulo= 31821&id_seccion=458&id_ejemplar=3272&id_revista=31

4. De Sanctis U, Machetta F, Razzano L, Dalmasso P, Grignolo FM. Corneal endotelial evaluation with 2 Noncontact Specular Microscopes and their semiautomated methods of Analysis. Cornea. 2006;25(5):501-6.

5. Delgado García JA. Reproducibilidad intra e interobservadores de los resultados de recuento endotelial con microscopia endotelial de no contacto TOPCON SP-3000P en la Fundación Oftalmológica de Santadar-Clínica Carlos Ardila Lulle (FOSCAL)- Centro Oftalmológico Virgilio Galvis. Universidad Industrial de Santander. Facultad de Salud. 2011 [citado 26 de enero de 2014]. Disponible en: http://repositorio.uis.edu.co/jspui/bitstream/123456789/10163/2/137806.pdf

6. Akiko H, Sakai H, Sawaguchi S, Akiko I, Tomidokoro A, Amano S, et al. Corneal endothelial cell density and associated factors in a population-based study in Japan: The Kumejima study. En: Am J Ophthalmol [Internet]. 2010 [citado 26 de enero de 2014];149(5):[aprox 4 p.]. Disponible en: http://www.ajo.com/article/S0002- 9394(09)00970-2/fulltext

7. Nasser MH. Densidad celular del endotelio corneal y en la morfología normal iraní ojos. BMC Ophthalmology [Internet]. 2006 [citado 26 de enero de 2014];6:[aprox 10 p.]. Disponible en: http://viaclinica.com/article.php?pmc_id=1456995

8. Molina Rey DF, Gómez A. Evaluación por décadas de edad del comportamiento de las células endoteliales corneales en población mexicana. Rev Mex Oftalmol [Internet]. 2005 [citado 26 de enero de 2014];79(2):[aprox 2 p.]. Disponible en: http://www.imbiomed.com.mx/1/1/articulos.php?method=showDetail&id_articulo= 31821&id_seccion=458&id_ejemplar=3272&id_revista=31