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Colegio de Medicos y Cirujanos República de Costa Rica
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2015, Number 614

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Rev Med Cos Cen 2015; 72 (614)

Cáncer anal

Gamboa PC
Full text How to cite this article

Language: Spanish
References: 10
Page: 135-139
PDF size: 63.30 Kb.


Key words:

anal cáncer, anal canal, anal margin, HPV, HIV, digital rectal examination, CT, abdominoperineal excision, chemoradiotherapy.

ABSTRACT

The anal cancer is a rare disease with a rising incidence over the past years. The risk factors identified are: HVP infection, HIV, cigarette smoking and immunosuppression. The most common clinical presentation is rectal bleeding. The physical exam includes digital rectal examination, which allows a clinical staging depending on the tumor size. The diagnosis is made histologically, a biopsy should be performed. Thoracic and abdominal CT assesses tumor extension and disseminated disease. The treatment prior to the 1970’s involved abdominoperineal resection, nowadays the standard care is chemoradiotherapy because of the high rate of tumoral regression and organ preservation leaving surgery as an option for residual disease patients.


REFERENCES

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  2. De Nardi, Paula; Carvello, Michele; Staudacher, Carlo. New approach to anal cancer: Individualized therapy based on sentinel lymph node biopsy. World J Gastroenterol. 2012; 18 (44): 6349-6356.

  3. Engstrom, Paul; Arnoletti, Juan; Benson, Al. et al. Anal Carcinoma. JNCCN. 2010; 8: 106-120.

  4. Ferrer, Manuel; Velasco, Francisco; Belda, Ricardo; Berenguel, María; Reina, Angel. Adenocarcinoma del canal anal. Revisión de conjunto. Cirugía Española. 2013; 91 (5): 281- 286.

  5. Glynne-Jones, Robert et al. Anal Cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Radiotherapy and Oncology. 2014; 111(3): 330-339.

  6. Glynne Jones, Robert; Norhover, J; Oliveira, J. Anal Cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Annals of Oncology. 2009; 20 (4): 57-60.

  7. Medical Advisory Secretariat. Anal dysplasia screening: an evidencebased analysis. Ontario Health Technology Assessment Series. 2007; 7 (4).

  8. Musio, Daniela; De Felice, Francesca; Raffetto, Nicola; Tombolini, Vincenzo. Management of persistent anal canal carcinoma after combined-modality therapy: a clinical review. Radiation Oncology. 2014; 9:39.

  9. Stanley, Margaret; Winder, David; Sterling, Jane; Goon, Peter. HPV infection, anal intra-epithelial neoplasia (AIN) and anal cancer: current issues. BMC Cancer. 2012; 12: 398.

  10. Uronis, Hope; Bendell, Johanna. Anal Cancer: an Overview. The Oncologist. 2007; 12 (5): 524-534.




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Rev Med Cos Cen. 2015;72