medigraphic.com
ISSN 1561-2996 (Electronic)
ISSN 0864-0289 (Print)

2015, Number 2

<< Back Next >>

Rev Cubana Hematol Inmunol Hemoter 2015; 31 (2)

Unusual bleeding in hemophilic patients

Castillo-González DC, Machín-García S, Macías-Pérez I, Agramonte-Llanes O, González-Otero A, Serrano-Mirabal J

Language: Spanish
References: 12
Page: 204-210
PDF size: 101.08 Kb.


ABSTRACT

Hemophilia is a serious hemorrhagic disease with marked phenotypic heterogeneity. Muscle and joint bleedings are the most common clinical manifestation and they stand out by the resultant chronic sequelae. However, there are other less frequent types of bleeding disorders that can be severe and disabling and the possibility to recognize them early avoids adverse consequences. We present two pediatric patients who attended the emergency service with bleeding events in unusual places: mediastinal, pulmonary and rectus. These patients were early diagnosed based on a detailed interview and physical examination supported by imaging studies such as radiography and ultrasound which enabled the appropriate handling of these bleedings with opportune replacement therapy and without further complications. It is evident that early diagnosis is the key element in monitoring patients with hemophilia to prevent complications of the disease.


REFERENCES

  1. Taillé C, Fartoukh M, Houël R, Kobeiter H, Rémy P, Lemaire F. Spontaneous Hemomediastinum Complicating Steroid-Induced Mediastinal Lipomatosis. Chest. 2001 Jul;120(1):311-3.

  2. Gupta P, Guleria S, Sharma S. Mediastinal haematoma: a rare complication following insertion of central venous catheter. Indian J Chest Dis Allied Sci. 2011 Oct-Dec;53(4):225-8.

  3. Quero-Valenzuela F, Piedra-Fernández I, Sevilla-López S, Cueto-Ladrón de Guevara A. Spontaneous hemomediastinum and hemothorax after dissecting bronchial artery aneurysm. Interact Cardiovasc Thorac Surg. 2011 Apr;12(4):619-21.

  4. Ali HA, Lippmann M, Mundathaje U, Khaleeq G. Spontaneous hemothorax: a comprehensive review. Chest. 2008 Nov;134(5):1056-65.

  5. Wilimas JA, Presbury G, Orenstein D, Dahl GV, Wang W, Dugdale M. Hemothorax and hemomediastinum in patients with hemophilia. Acta Haematol. 1985;73(3):176-8.

  6. Selim B, Lane CR, Rubinowitz AN, Siner JM. Spontaneous hemothorax and recurrent hemoptysis in a 26-year-old man with skin lesions. Chest. 2010 Feb;137(2):480-3.

  7. Rasaretnam R, Chanmugam D, Sivathasan C. Spontaneous haemothorax in a mildhaemophiliac. Thorax. 1976 Oct;31(5):601-4.

  8. Ylmaz S, Oren H, Irken G, Atabay B, Duman M, Ylmaz E, et al. Life-threatening mediastinal-retroperitoneal hemorrhage in a child with moderate hemophilia A and high inhibitor titer: successful management with recombinant activated factor VII. J Pediatr Hematol Oncol. 2005 Jul;27(7):400-2.

  9. Gidaris D, Economou M, Valeri R, Gombakis N, Athanasiou-Metaxa M. Successful treatment of a spontaneous haemothorax with recombinant factor VIIa in a haemophilic child with inhibitors. Hippokratia. 2010 Oct;14(4):289-90.

  10. Alla V, Karnam SM, Kaushik M, Porter J. Spontaneous Rectus Sheath Hematoma. West J Emerg Med. Feb 2010;11(1):76–9.

  11. Kocayigit I, Can Y, Sahinkus S, Aydın E, Vatan MB, KılıcH, et al. Spontaneous rectus sheath hematoma during rivaroxaban therapy. Indian J Pharmacol. 2014 May-Jun;46(3):339–40.

  12. Galyfos G, Karantzikos G, Palogos K, Sianou A, Filis K, Kavouras N. Spontaneous rectus sheath hematoma in the elderly: an unusual case and update on proper management. Case Rep Emerg Med. 2014;2014:675678. doi: 10.1155/2014/675678.




2020     |     www.medigraphic.com