Torres-Gutiérrez JL, Rodríguez- Rangel EI, Torres-Luna S

Language: Spanish
References: 25
Page: 27-32
PDF size: 554.61 Kb.

ABSTRACT

Background: Frailty is a problem particularly prevalent in patients older than 75 years, and hypoalbuminemia is thought to increase the risk of vulnerability and mortality.
Objective: To determine the impact of hypoalbuminemia in survival of frail patients older than 75 years.
Material and Method: A descriptive, observational, cross-sectional and retrospective study was performed. We analyzed records of patients with diagnosis of frailty, and at least one determination of serum albumin for the last 6 years. Patients were divided into 2 groups: frail patients with hypoalbuminemia (albumin equal to or less than 3.5 g/ dL, group 1) and patients with normal serum albumin levels (albumin greater than 3.5 g/dL, group 2).
Results: We evaluated 872 patients. 136 patients were identified with frailty (15.5%); 13 did not have albumin determinations, and therefore were excluded. The average age was 82.62 years (range 75 to 98 years). 80 patients were female (65%) and 43 were male (35%). From the final study group of 123 patients, we identified 97 patients (79%) with hypoalbuminemia. Occurred 79 deaths (64%) during the follow-up period of 72 months, 67 (85%) in group 1 (odds ratio [OR] 2.60, p=0.02) and 12 (15%) in group 2 (OR 2.09, p=0.02).
Conclusions: hypoalbuminemia is associated with higher risk of death in frail elderly patients over 75 years of age.

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