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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2005, Number 11

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Ginecol Obstet Mex 2005; 73 (11)

Associated factors to abnormal glucosylated hemoglobin in the postpartum period

Gómez CZ, Pérez MJJ, Panduro BJG, Fletes RVM, Vásquez GEM, Troyo SR, Cárdenas MM
Full text How to cite this article

Language: Spanish
References: 9
Page: 591-595
PDF size: 56.91 Kb.


Key words:

glucosylated hemoglobin, puerperium, associated factors.

ABSTRACT

Objective: To demonstrate the association between risk factors and abnormal glucosylated hemoglobin detected in women during the postpartum period.
Patients and methods: A case and control study was carried out at the Hospital Civil de Guadalajara Dr. Juan I. Menchaca during six months. Glucosylated hemoglobin and glucose concentration from 160 fasting women with a pregnancy ≥ 28 weeks was obtained during the postpartum period. With an odds ratio and confidence interval (95%) the epidemiological meaning of risk factors was identified.
Results: The abnormal glucosylated hemoglobin was significantly associated to: single, separated and divorced women (p ‹ 0.05); major frequency of previous caesarean (OR: 2.78, IC 95%:1.25-6.22), p= 0.006, and higher proportion of children with congenital malformations (OR: 12, IC 95%: 1.38-104), p = 0.01. In the group cases 48% of caesareans was associated to probable gestational diabetes: moderate preeclampsia, eclampsia, fetal macrosomy, and preterm deliveries.
Conclusion: It is necessary to make an early detection of risk factors associated to abnormal glucosylated hemoglobin and to prevent adverse effects as congenital malformations and clinical complications that increase the incidence of caesarean.


REFERENCES

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  2. Forsbach G, González F, Vázquez J, et al. Morbilidad materna y fetal en un grupo de mujeres con diabetes gestacional. Ginecol Obstet Mex 1999;67:272-5.

  3. Catalano P, Larraine H, Sacid B, Amini P, Satish C, Calan E. Longitudinal changes in glucose metabolism during pregnancy in obese women with normal glucose tolerance and gestational diabetes mellitus. Am J Obstet Gynecol 1999;180: 903-16.

  4. Widness J, Schwartz H. Glycohemoglobin in postpartum women. Obstet Gynecol 1981;57:414-21.

  5. Partida-Hernández G. Hemoglobina glucosilada (HbA1) en el embarazo. Ginec Obstet Mex 2000;68:420-4.

  6. Chandalia H.B, Krishnaswamy P.R. Glycated hemoglobin. Diabetes 2002;83:1522-32.

  7. Jovanovich L. The diabetic pregnancy: a clinical challenge. Symposium of the diabetes and pregnancy council. Proceedings of the 60th scientific sessions of the Am Diabetes Assoc; San Antonio Texas, 2000;June 2-11.

  8. ACOG. Gestational Diabetes. Practice Bulletin No. 30. American College of Obstetricians and Gynecolgists. Obstet Gynecol 2001;98:525-38.

  9. Fiorelli S, Cejudo E, Smith A. Diabetes mellitus en el embarazo. En: Alfaro H, editor. Complicaciones médicas en el embarazo. 2ª ed. México: Interamericana, 1996;p:149-57.




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C?MO CITAR (Vancouver)

Ginecol Obstet Mex. 2005;73