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2016, Number 2

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Rev Hematol Mex 2016; 17 (2)

Fisher-Evans or Evans syndrome

Cimá-Castañeda MÁ, Ayala-López PM, Lara-Palacios MI, Abblitt-Luengas SM, Jiménez-Báez MV

Language: Spanish
References: 11
Page: 144-149
PDF size: 312.74 Kb.


ABSTRACT

Fisher-Evans syndrome is the manifestation of an immune hemolytic anemia that may be simultaneous or subsequent to an immune thrombocytopenia sometimes attached with immune neutropenia. It has been estimated that between 0.8 to 4% of patients with immune thrombocytopenia or immune hemolytic anemia presents this syndrome. Autoimmune diseases have been associated with virus infections. We report the case of a 58-year-old male with a suspected aplastic anemia diagnosed with an evolution of three weeks with a viral clinical manifestations. Epstein-Barr virus profile concluded with an acute mononucleosis. VGM hemolysis positive with indirect bilirubin of 2.1 g/dL, febrile reactions with secondary pan-agglutination to immune thrombocytopenic purple, direct Coombs positive, high HDL. Evans syndrome diagnosis was stablished. Bone marrow aspiration; discreetly decrease megakaryocytes present, morphologically show immature, polysegmentation of neutrophils and cell gigantism. Currently there are no reports of the prevalence of this syndrome in Mexico.


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