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2016, Number 4

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Acta Med 2016; 14 (4)

Mediastinal lymphoma

Gallegos GAC, Sánchez OR, Espinosa PK, Hurtado MR
Full text How to cite this article

Language: Spanish
References: 6
Page: 240-243
PDF size: 304.26 Kb.


Key words:

Mediastinal lymphoma, mediastinal mass, vena cava syndrome.

ABSTRACT

Primary lymphoma of the mediastinum is a diffuse large cell lymphoma of B-cell type that occurs most often between the third and fourth decades of life, with a predominance in women. This kind of lymphoma corresponds to 2.4% of all lymphomas in adults. The clinical presentation of mediastinal lymphoma is often an emergency because of its rapid growth and the risk of vena cava syndrome. The main diagnostic procedure is an incisional biopsy by mediastinoscopy or thoracoscopy. The optimal treatment for these tumors is not entirely standardized, it depends on the general health condition of the patient. Chemotherapy schemes depend largely on the size of the tumor and if adjuvant radiotherapy is considered.


REFERENCES

  1. Martelli M, Ferreri AJ, Johnson P. Primary mediastinal large B-cell lymphoma. Crit Rev Oncol Hematol. 2008; 68: 256-263.

  2. Shipp MA, Aquino SL, Harris NL. Case records of the Massachusetts General Hospital. Case 12-2005: a 30 year old woman with mediastinal mass. N Engl J Med. 2005; 352: 1697-1704.

  3. Lamarre L, Jacobson JO, Alsenberg AC, Harris NL. Primary large cel lymphoma of the mediastinum. A histologic and immunophenotypic study of 29 cases. Am J Surg Pathol. 1989; 13: 730-739.

  4. Kolonić SO, Dzebro S, Kusec R, Planinc-Peraica A, Dominis M, Jaksić B. Primary mediastinal large B-Cell lymphoma: a single-center study of clinicopathologic characteristics. Int J Hematol. 2006; 83: 331-336.

  5. Abou-Elella AA, Weisenburger DD, Vose JM, Kollath JP, Lynch JC, Bast MA et al. Primary mediastinal large B-cell lymphoma: a clinicopathologic study of 43 patients from the Nebraska Lymphoma Study Group. J Clin Oncol. 1999; 17: 784-790.

  6. Chávez MR, Carnot UJ, de Castro AR, Muñío PJ, Pérez RG, Núñez QA. Características clínicas y resultados terapéuticos de linfomas no Hodgkin de células grandes B primarios. Revista Cubana de Medicina. 2011; 50 (2): 157-166.




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Acta Med. 2016;14