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ISSN 2594-1518 (Electronic)
ISSN 1405-0099 (Print)

2016, Number 2

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Cir Gen 2016; 38 (2)

Anal plasmablastic lymphoma. Report of two cases

Grijalva-Santana C, San Marcos-Romero D, Jiménez-Bobadilla B, Mendoza-Ramírez S, Reyes-Hansen MD, Cosme-Reyes C

Language: Spanish
References: 10
Page: 78-82
PDF size: 296.95 Kb.


ABSTRACT

Plasmablastic lymphoma (PBL) is a type of lymphoma with fast and aggressive growth considered a variant of non-Hodgkin’s lymphoma. The relative risk of developing this type of lymphoma in human immunodeficiency virus (HIV) positive patients is 80 to 110 times higher than in the general population. Lymphomas in HIV-positive patients have also been strongly associated with virus infection, which suggests an important role of those in the pathogenesis of these lymphomas. Two patients diagnosed with PBL in the anal region were identified in the medical records of the Coloproctology Service of the Hospital General México. We review the clinical course of these patients, their imaging studies and pathology reports supplemented with immunohistochemical reactions. Plasmablastic lymphoma in the anal canal is a rare disease with high mortality in the first year and a poor response to chemotherapy. There are a few cases reported in the literature. We present the ones of these two patients diagnosed the same year. These types of tumors are often masked by other anorectal disorders.


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