Pérez-Reyes M, Benavides-Aguilar O, Morales-Arias S

Language: Spanish
References: 14
Page: 8-12
PDF size: 232.99 Kb.

ABSTRACT

Background. Neurological and physiological deficit have been reported in the brain in developmental dyslexia, manifested as biochemical changes in the brain, able measure of magnetic resonance spectroscopy.
Objective. Observed biochemical differences between dyslexic and controls in the temporoparietal lobe and circumvolution temporal first for magnetic resonance spectroscopy bilaterally, in 10 child dyslexic and 5 controls, means test t Student.
Material and method. A transversal, prospective, descriptive and comparative study by means register of patients consulting room neuropediatric of the Medical Specialties unit, with ages between 7 y 12 years old, both sex and realized magnetic resonance spectroscopy in temporo-parietal lobe and temporal circumvolution first bilaterally.
Results. We found no such significant dominate interhemisferic, there was no significant relation between in the control and dyslexic. We found biochemical differences between dyslexic and controls in the right temporo-parietal lobe (ratio of N-acetylaspartate-containing compounds (NAA) to Creatine (Cr), NAA/Cr, p = 0.0239), and left temporal circumvolution Cho/Cr, p = 0.028. There was no significant in the changes biochemical dyslexic and control bilaterally.
Conclusions. Standardize and attention biophysics aspects in obtained images of magnetic resonance spectroscopy, to permit complement evaluation dyslexic pediatric patients. Although, in our study the model is little as document differences significant statistics, achieve observed alterations metabolically local in the left temporal circumvolution first and right temporo-parental that help understanding developmental dyslexia.

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