Domínguez-Sandoval Z, Millán-Catalán MÁ, González-Galván LM, Mejía-Galeana B, Ruiz GAC, Villagómez-García I, León-Hernández S

Language: Spanish
References: 15
Page: 237-247
PDF size: 228.27 Kb.

ABSTRACT

Objective: To describe and analyze the factors associated with the development of ischemic heart disease in patients previously diagnosed with subclinical atherosclerosis in follow-up to four years.
Material and methods: An observational, descriptive and retrospective study including 52 diabetic patients diagnosed with subclinical atherosclerosis followed to four years, describing the factors associated with the development of ischemic heart disease was designed. Patients who left the track were excluded, lost or died. mean, standard deviation, frequencies and percentages with a CI 95% were determined. discriminant analysis model for men and women separately applied Wilks' lambda, Chi-square and Fisher equation with values of p ‹ 0.05.
Results: Of the total sample of patients with DM2, 36.5% were men and 65.5% women with an average age of 58.0 ± 7.8 years. the subclinical atherosclerosis was found in 63.6% (p=0.57), of which 7 developed ischemic heart disease, 20.5% (p=0.57). Globally they change in BMI, HbA1c and serum creatinine with p ‹ 0.05 in monitoring patients to 4 years were observed. As outcome variables were identified: development of ischemic heart disease, angina pectoris, and events cardiovascular adverse mayors in 13.7, 21.6 and 17.6% respectively of the total population. Finally, they were identified as risk factors for developing ischemic heart male gender, presence and years of hypertension and smoking, dyslipidemia and present complications of DM2 all with p ‹ 0.05.
Conclusion: Long-term studies are required, with a larger number of patients. A case-control study is suggested to determine which type of variables are associated with increased risk of cardiovascular events in diabetic patients.

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