Popuche PDR, Santana BDA, Rocha AC, Peña-Sánchez ER, Malca TN

Language: Spanish
References: 14
Page: 17-29
PDF size: 468.28 Kb.

ABSTRACT

Ischemic cerebrovascular or stroke (stroke) disease today can be considered an epidemic and a first order public health problem. Some studies claim that the elevation of uric acid plays a protective role in the evolution of acute stroke. There are also studies where the precise relationship between the concentrations- as an independent factor- and the favorable evolution of stroke remains unclear.
Objetive: To determine whether there is a correlation of serum uric acid level and neurological recovery with the result of the scale of NIHSS in patients with ischemic cerebrovascular accident in a hospital in Lambayeque, January-May 2016.
Methods: The population consisted of all patients in the neurology department of the National Hospital Almanzor Aguinaga Asenjo. The sampling was non-probabilistic consecutive obtaining a sample of 85 patients with ischemic stroke patients admitted for emergency to the Neurology Service between the months of January to May 2016. Patients with a first episode of stroke and ischemic time of less than 24 hours hospitalization. the NIHSS scale was applied and the AC outlet. serum uric patient admission and discharge control (10 days in hospitalization).
Results: The mean age of studied subjects was 71.8 ± 13.4 years, predominantly male (69.41%), the predominant comorbidity was hypertension (45.88%), 28.3% of patients have improved blood and patients not improved by 71.67% had hypertension hypertension. A higher level of uric acid on admission, the condition is worst at discharge and at higher levels of uric acid on admission, the condition is worst at discharge. Patients who presented with hypertension the possibility of improvement is reduced by 69%. The possibility of improvement increased 2.87 times compared to those who had an increase of uric acid.
Conclusions: the results provide strong support to the hypothesis that uric acid is a marker of the severity of ischemic vascular brain accident, evidence to serum uric acid as an independent prognostic factor in patients with ischemic stroke.

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