Uribe-Álvarez C, Chiquete FN

Language: Spanish
References: 10
Page: 51-55
PDF size: 1184.31 Kb.

ABSTRACT

According to the World and Health Organization (WHO), 17% of the worldwide reported infectious diseases are vector- borne. One alternative for blocking the transmission of these infectious agents is to infect the vectors with the endocellular bacterium Wolbachia. Several studies have shown that Wolbachia shortens mosquitos’ lifespan and increases their resistance to some virus like Dengue, Zika or Chikungunya. Wolbachia also causes cytoplasmic incompatibility, so, when Wolbachia-infected male mosquitoes are released among an uninfected female population, the production of an offspring is not viable and the mosquito population decreases drastically. This article includes an overview of the most common vector-borne infectious diseases as well as a review of the use of Wolbachia as a possible tool for controlling the spread of vector-borne diseases.

REFERENCES

1. World Health Organization [portal en internet]. Vector Borne Diseases. [Actualizado: octubre de 2016]. Geneva, Switzerland. Disponible en: http://www.who.int/mediacentre/ factsheets/fs387/en/

2. World Health Organization. World Malaria Report 2016. Geneva: WHO. ISBN 978-92-4-151171-1. Disponible en: https://goo.gl/BgU6NY

3. Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL et.al. The global distribution and burden of dengue. Nature. 2013;496:504-7. doi:10.1038/nature12060.

4. Dennis, DT, Gage KL, Gratz N, Poland JD, and Tikhomirov E. Plague Manual. Epidemiology, Distribution, surveillance and Control. Geneva, Switzerland: World Health Organization; 1999. 172 pp. Figura 2. Resultados de la cruza de mosquitos infectados con Wolbachia (rojo)

5. World Health Organization. A global brief on vector borne diseases. Document number: WHO/DCO/WHD/2014.1. Geneva, Switzerland; 2014. 56 pp.

6. Walker T, Moreira LA. Can Wolbachia be used to control malaria? Mem Inst Oswaldo Cruz [Internet]. 2011;106( Suppl 1):212-7.

7. McMeniman CJ, Lane RV, Cass BN, Fong AWC, Sidhu M, Wang YF, et al. Stable Introduction of a Life-Shortening Wolbachia Infection into the Mosquito Aedes aegypti. Science. 2009;323(5910):141-4.

8. Caragata EP, Dutra HL, Moreira LA. Inhibition of Zika virus by Wolbachia in Aedes aegypti. Microbcell. 2016; 3(7):293-5.

9. Maistrenko OM, Serga SV, Vaiserman AM, Kozeretska IA. Effect of Wolbachia Infection on Aging and Longevity- Associated Genes in Drosophila. En: Vaiserman AM, Moskalev AA, Pasyukova EG (editores). Life Extension: Lessons from Drosophila (Healthy Ageing and Longevity). Switzerland: Springer; 2015.

10. Werren JH, Baldo L, Clark ME. Wolbachia: master manipulators of invertebrate biology. Nature reviews. Microbiology. 2008;6:741-51.